ATP-driven active transport

In this  case  the  energy  needed  for  the  transport  of the  molecule  across  the membrane  is  derived  from  the  coupled  hydrolysis  of  ATP,  for  instance  the movement of Na⁺  and K⁺  ions through the Na⁺/K⁺   -ATPase. All cells preserve a high internal concentration   of K ⁺and a low internal concentration   of Na+ . The resulting  Na⁺   /K⁺ gradient  across  the  plasma  membrane  is  important  for  the active  transport  of  certain  molecules and  the  maintenance  of  the  membrane electrical potential. The movement across the membrane of Na⁺   , K⁺   , Ca²⁺  and H⁺, as well as a number of other molecules is directly coupled to the hydrolysis of ATP.