RNA polymerases:
Expects prokaryotes where all RNA is synthesized through a single RNA polymerase, the nucleus of a eukaryotic cell has three RNA polymerases responsible for transcribing various kinds of RNA.
- RNA polymerase I (RNA Pol I) is located in the nucleolus and transcribes the18S, 28S and 5.8S rRNA genes.
- RNA polymerase II (RNA Pol II) is situated in the nucleoplasm and transcribes protein-coding genes, to yield pre-mRNA, and also the genes encoding small nucleolar RNAs (snoRNAs) included in rRNA processing and small nuclear RNAs (snRNAs) included in mRNA processing, unlike for U6 snRNA.
- RNA polymerase III (RNA Pol III) is also situated in the nucleoplasm. It transcribes the genes for 5S rRNA, tRNA, U6 snRNA, and the 7S RNA related with the signal recognition particle (SRP) included in the translocation of proteins across the endoplasmic reticulum membrane.