Calculate the distribution ratio:
Problem:
The distribution coefficient of a certain weak acid between benzene and water is 100. Calculate the distribution ratio for this acid at pH = 7.00 of the aqueous phase. Ka = 1.00 × 10-6 for the acid in the aqueous phase and the acid remains as a monomer in the benzene phase.
Answer:
D = 100(1.00 × 10 -7 )/ (1.00 ×10 -7 ) + (1.00 × 10 -6 ) = 9.09