Activation domains:

Unlike  DNA  binding  domains  and  dimerization  domains,  no  general  structural motifs have since been identified  in the activation  domains  of diverse transcription factors. Some kinds of activation domain are as follows:

- acidic activation   domains   are  rich  in  acidic  amino  acids aspartic   and glutamic acids. For instance, mammalian glucocorticoid receptor proteins contain this kind of activation domain;

- An glutamine-rich domains for instance as in SP1 transcription factor;

- An proline-rich domains for example as in c-jun transcription factor