Sulfonylation Assignment Help

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Sulfonylation:

In an identical reaction to acylation, primary and secondary amines (both aromatic and aliphatic) can be treated with a sulfonyl chloride to provide a sulfonamide. Tertiary amines do not provide a stable product and are recovered not changed.

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Figure: Reaction of benzenesulfonyl chloride with (a) primary amine; (b) secondary amine.

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