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(+) and (-):
The assignment of an asymmetric center like R or S has nothing to do with any direction the molecule rotates plane-polarized light. Optical rotation can just only be ascertained experimentally. Through convention, molecules that rotate plane-polarized light clockwise are described as (+) or d. Molecules that rotate plane-polarized light counterclockwise are identified as (-) or l. The R enantiomer of lactic acid is found to rotate plane-polarized light counterclockwise and thus this molecule is identified as (R)-(-)-lactic acid.
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