Examples of quantitative determinations:
Examples of quantitative determinations by NMR are:
Analysis of Multicomponent Mixtures: A mixture of aspirin, phenacetin and caffeine in commercial analgesic preparation can be analysed by NMR with a relative error of 1 to 3%. Similarly a mixture of benzene, heptane, ethylene glycol and water can be precisely and rapidly determined by NMR.
Elemental Analysis: Though NMR is not routinely used for the determination of total elemental concentration yet, within principle it could be used for given NMR active nucleus in a sample. The integrated NMR intensities of the proton peaks for a large number of organic compounds can be used for the accurate quantitative determination of total hydrogen atoms in an organic mixture.
Organic Functional Group Analysis: A useful application of NMR is the determination of functional groups such hydroxyl groups (-OH) in alcohols (ROH) and phenols (C6H5OH), aldehydes, carboxylic acids, olefinic and acetylenic hydrogens, amines and amides with relative error of 1 to 5% range.