Classical electrophysiology

Electrophysiology is the learning of the electrical properties of biological tissues and cells. It includes measurements of electric current or voltage change on a broad variety of scales from single ion channel proteins to overall organs such as the heart. In neuroscience, it involves measurements of the electrical activity of neurons and particularly action potential activity. To Recordings of large-scale electric signals from the nervous system like as electroencephalography may also be referred as electrophysiological recordings.

Electrophysiology is the branch and science of physiology which pertains to the flow of ions in biological tissues and in particular, to the electrical recording methods which enable the measurement of this flow. Classical electrophysiology methods include placing electrodes into several preparations of biological tissue. The electrophysiologist may choose not to insert the tip into a single cell. Alternate, the electrode tip may be left in continuity with the extracellular space. If the tip is small enough like a configuration may allow indirect observation and recording of action potentials from a single cell and is termed single-unit recording.