Acetylcholine

Acetylcholine (frequently abbreviated as ACh) is the main excitatory neurotransmitter at nematode neuromuscular connections i.e. in both the peripheral nervous system (PNS) and central nervous system (CNS) in most organisms including the humans. The elegans nervous system discharges the acetylcholine. Throughout a combination of drug-resistance selections, forward genetics, and genomic analysis, mutants have been specified for all of the steps specially needed for cholinergic function. These involve two enzymes, two transporters, and a bewildering assortment of the receptors. The Cholinergic transmission is included, directly or indirectly, in many C. The elegans behaviors, involving feeding, locomotion, egg laying, and male mating.

In cardiac tissue the acetylcholine neurotransmission has an inhibitory effect that lowers heart rate. Though, acetylcholine also behaves as an excitatory neurotransmitter at neuromuscular junction in the skeletal muscle.