Selection of liquid phase:

The selection of liquid phase depends upon various considerations. The liquid phase selection depends on the composition of the sample. It is expected in which the type of solutes likely to be present in the sample is known before the analysis is beginning. The more one knows about a sample, simpler it is to select the proper column and operating temperatures. For an efficient normal separation, the liquid phase should be same in chemical structure to the solutes of the sample. For instance, hydrocarbon compounds are best separated along with a hydrocarbon solvent. Paraffins are best separated on squalane (a long chain hydrocarbon). Polar solutes such like alcohols are best separated on a polar - Hailcomid (an amide) solvent. Table provides the names of general liquid phases in GC separations.

Table :  Recommended Liquid Phases by Sample Types