Chemical Interferences:

These involve interferences because of ionisation, creation of low volatility compounds, dissociation, etc. During atomisation within the flame, various reactions occur resulting within the creation of analyte compounds that decrease atomic population in the cell. Most significant chemical interference is because of anions and form atom of compounds of low volatility from the analyte element. For instance, the refractory elements like as W, U, Ti, V, Mo, Zr and elements such as B, Al, and Fe might combine with O and OH species within the flame producing thermally stable oxides and hydroxides. Same, absorbance because of Ca is decreased in presence of phosphate since of the creation of calcium phosphate having low volatility.

Such interferences could be prevented through increasing the flame temperature whence these interfering compounds are decomposed. Within some cases chemical interferences might be eliminated through using a releasing agent which reacts with interfering species and prevents its reaction along with the analyte element. For instance, in the determination of Ca, Sr and La could be used as releasing agents to minimise phosphate interference as these would react preferentially along with the phosphate.