Moving Belt Interface:

In this case, effluent is placed by spray deposition onto a continuous moving belt that is woven from ultrafine quartz fibre. As the spray deposition is essentially a dry process, solvent need not be removed. The belt passes through two successive vacuum locks where the pressure is reduced to 0.1 Torr before moving into the ion source housing of the fast ion bombardment (FAB) mass spectrometer. After the belt leaves the FAB unit, it exits through the two vacuum chambers. Any residual sample or solvent is removed by a wash bath. Though moving belt interface is cumbersome but it can be used with magnetic sector or quadruple instruments and in either of the election-impact or chemical ionization mode.

The technology and value of the HPLC-mass spectrometry has increased in parallel with the developments in mass spectrometry. As of now very accurate molecular mass measurements can be made using new generation of compact time of flight spectrometers whose performance is comparable to much larger and more expensive magnetic sector instruments.