Radial loops:
When the chromosomes are depleted of histones they are seen to have a central fibrous 'protein scaffold' or nuclear matrix to which the DNA is attached in loops. Thus, in vivo it seems such as in which the next order of packaging includes the attachment of the 30 nm fiber to multiple locations on this central protein scaffold in a series of radial loops. Little is called to how this structure is organized.
![458_Radial loops.png](https://www.expertsmind.com/CMSImages/458_Radial%20loops.png)
figure: Attachment of the 30nm fiber to a central protein scaffold with the loops arranged radially around the scaffold. The diagram on the right shows a representational cross-section through a chromosome.