Nucleotides Assignment Help

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Nucleotides:

The nucleotide is a phosphate ester of a nucleoside. It consists of a phosphate group connect to a nucleoside at the hydroxyl set attached to the C-5 of the sugar which is it is a nucleoside a 5'-nucleotide or 5'-phosphate. The primed number denotes the atom of the sugar to that the phosphate is bonded. In the DNA nucleotides have deoxyribose as the sugar and hence are known as deoxynucleotides. The Deoxynucleotides may   have  a  single  phosphate group  (deoxynucleoside 5′-monophosphates, dNMPs) two phosphate groups (deoxynucleoside 5′- diphosphates, dNDPs) and three phosphate sets (deoxynucleoside 5′- triphosphates, dNTPs).  The Deoxynucleoside triphosphates are the precursors for DNA synthesis. That are deoxyadenosine 5′-triphosphate (dATP), deoxyguanosine 5′-triphosphate (dGTP) and deoxycytidine 5′-triphosphate (dCTP) and deoxythymidine 5′-triphosphate (dTTP).  

In  each  case  the 'd' in  the abbreviation (for example in dATP) indicates that the sugar in the nucleotide is deoxyribose.  During DNA synthesis, two of the phosphates of each deoxynucleotide are split off (as pyrophosphate) so which only a single phosphate (the    phosphate) is incorporated into DNA.

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