Transcriptomics and proteomics Assignment Help

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Transcriptomics and proteomics:

Through analogy with the word 'genome', the transcriptome is all of the RNA series transcribed from a cell's genome and the proteome is all of the expressed proteins of that cell. While all of the cells of an organism like as a human contain essentially the same genome, the transcriptome and proteome of variant cell kinds varies depending on the genes which are expressed. For instance, the transcriptome and proteome of a liver cell are unique from that of a neurone.  The Trancriptomics refers to studies of the transcriptome and involves, for instance, the use of DNA microarrays to determine expression profiles.   Proteomics the study of the proteome and currently relies heavily on using 2-D gel electrophoresis  to divided the proteins expressed through a cell or tissue,  followed  through mass spectrometry  to produce  peptide  mass finger- prints of each protein.  The expressed proteins can then be identified through comparing these fingerprints with databases of fingerprints, involving those predicted from DNA sequence data.   Given the huge scale of such methods, several of these process are necessarily automated.

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