Replication of chromatin:
Whenever a chromosome is replicated the replication machinery passes by the nucleosomes without erasing the histones from the DNA. How this occurs is since not fully understood. Together of the daughter DNA molecules in which result from replication have old histones bound to them but overall, since the amount of DNA has now doubled more histones are required to package the DNA rightly into nucleosomes. Not surprisingly, thus, the S phase of the cell cycle is also the time when huge amounts of histones are synthesized.
![338_Replication of chromatin.png](https://www.expertsmind.com/CMSImages/338_Replication%20of%20chromatin.png)
figure: Replication of telomeric DNA. Telomerase has a bound RNA molecule that is used as template to direct DNA synthesis and hence extension of the ends of chromosomal DNA.