The Vilsmeier-Haack reaction (also known as the Vilsmeier reaction) is the chemical reaction of a substituted amide (1) with phosphorus oxychloride and an electron-rich arene (3) to give an aryl aldehyde or ketone (5). The reaction is named for the Anton Vilsmeier and Albrecht Haack.
![1461_Vilsmeier–Haack-reaction.png](https://www.expertsmind.com/../CMSImages/1461_Vilsmeier–Haack-reaction.png)
Reaction Mechanism -
![1902_Vilsmeier–Haack-reaction-mechanism.png](https://www.expertsmind.com/../CMSImages/1902_Vilsmeier–Haack-reaction-mechanism.png)
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