Upjohn dihydroxylation is a chemical reaction changing an alkene to a cis vicinal diol, and was invented by V. VanRheenen, R. C. Kelly and D. Y. Cha of the Upjohn Company, USA in the year 1976. It is a catalytic system utilising N-Methylmorpholine N-oxide (NMO) as stoichiometric re-oxidant for the Osmium tetroxide, and is better than previous catalytic methods.
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