Hooker reaction Assignment Help

Assignment Help: >> Chemical Reactions - Hooker reaction

In Hooker reaction (1936) an alkyl chain in a certain naphthoquinone (phenomenon initially observed in the compound lapachol) is reduced by one methylene unit like carbon dioxide in every potassium permanganate oxidation.

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Mechanistically oxidation causes ring-cleavage at the alkene group, extrusion of carbon dioxide in decarboxylation with following ring-closure.

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