Directed ortho metalation Assignment Help

Assignment Help: >> Chemical Reactions - Directed ortho metalation

Directed ortho metalation (DoM) is an modification of electrophilic aromatic substitution in which electrophiles joins themselves completely to the ortho- position of a direct metalation group or DMG by the intermediary of an aryllithium compound. The DMG interacts with lithium by a hetero atom. Illustrations of DMG's are the methoxy group, an amide group and a tertiary amine group.

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Ordinary Electrophillic Substitution -

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