In carbohydrate chemistry carbohydrate acetalisation is a chemical reaction and a very efficient means of giving a protecting group. The example under shows the acetalisation reaction of D-ribose 1. With acetone or 2,2-dimethoxypropane as the acetalisation reagent the reaction is below thermodynamic reaction control and results in formation of pentose 2. The later reagent in itself is an acetal and thus the reaction is truly a cross-acetalisation.
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