Biosynthesis of amino acids:
Microorganisms and Plants can synthesize all of the 20 standard amino acids. Mammals, moreover, cannot synthesize all 20 and must acquire some of them in their diet. Those amino acids which are supplied in the diet are referred to as essential, while the remainder which can be synthesized through the organism are termed nonessential. This designation refers to the required of an organism under a particular group of conditions. In the humans nonessential amino acids are Arg, Gly, Asn, Ala, Cys, Asp, Pro, Glu, Gln, Ser and Tyr, therefore the essential ones are Leu, His, Ile, Thr, Lys, Met, Phe, Trp and Val for the structures of the 20 standard amino acids. The ways for the biosynthesis of amino acids are diverse and frequently vary from one organism to another. Though, they all have an important feature in general: their carbon skeletons come from key intermediates in middle metabolic pathways. The amino acids can be grouped together into six biosynthetic pathways depending on the intermediate from that they are derived. the main amino group commonly comes from transamination of glutamate.