Alkylation of Terminal Alkynes:
Terminal alkynes
A terminal alkyne is described like an alkyne having a hydrogen substituent as shown in figure.
![2001_Alkylation of Terminal Alkynes.png](https://www.expertsmind.com/CMSImages/2001_Alkylation%20of%20Terminal%20Alkynes.png)
Figure: Terminal alkyne.
This hydrogen substituent is acidic and can be eliminated with strong base (for example sodium amide NaNH2) to generate an alkynide. This is an instance of an acid-base reaction.
![47_Alkylation of Terminal Alkynes1.png](https://www.expertsmind.com/CMSImages/47_Alkylation%20of%20Terminal%20Alkynes1.png)
Figure: Reaction of a terminal alkyne with a strong base.