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Zearalenone
It was first isolated as the agent responsible for vulvovaginitis in pigs has very little acute toxicity, but there should be some concern about chronic exposure to a compound known to be estrogenic. It may be produced, together with DON and other trichothecenes, in a wide range of cereals including corn, barley and wheat.
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Neurological symptoms and signs occur in 30 to 40 per cent of patients with IE, are more frequent when IE is caused by S. aureus, and are associated with increased mortality rates.
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