Why TPP and TTP are vital for the nerves and cardiac tissues?

TPP and TTP are interconvertible and arc involved in carbohydrate metabolism. As discussed above, when there is insufficient thiamin, the overall decrease in carbohydrate metabolism and its interconnection with amino acid metabolism (via a-keto acids) has severe consequences, such as a decrease in the formation of acetylcholine for neural function. Thus, deficiency in the tissues affects energy inetaholism in nervous tissue and cardinc muscle.