Why the vast majority of segregation errors in human patient, Biology

Assignment Help:

Which of the following defines why the vast majority of segregation errors in human patients include the two sex chromosomes (XXY, XO, XYY) or chromosome 21 (triple 21)?

A. The centromeres of these three chromosomes lack attachment sites for spindle microtubules therefore leading to a higher than normal segregation error rate.

B. These three chromosomes have the highest probability to be mis-segregated during anaphase I and  II of meiosis.

C. Cells are more likely to survive with abnormal numbers of these three chromosomes whereas segregation errors of the other 20 human chromosomes are completely lethal.

D. Chromosome 21 as well as both sex chromosomes lack sequences that are recognized by proteins of the spindle assembly checkpoint (SAC). Thus the cell proceeds to anaphase even if these three chromosomes have failed to reach the metaphase plate.

 


Related Discussions:- Why the vast majority of segregation errors in human patient

Solutions of hydrocarbons evaporate at room temperature, The fact that some...

The fact that some pure solutions of hydrocarbons do not readily evaporate at room temperature is a result of Select one: a. London dispersion forces. b. The hydrophobic effe

What are the symptoms of rheumatic heart disease, Q. What are the symptoms ...

Q. What are the symptoms of Rheumatic Heart Disease? Symptoms generally appear after 1 to 6 weeks of the fever and sometimes the infection may have been too mild to have been r

Differance among subphylum chaetognatha and urochordata, Explain differance...

Explain differance between Subphylum Chaetognatha and Subphylum Urochordata? Subphylum Chaetognatha: Larval stages of this small group share some of the characteristics with

Explain the potential benefits of micro nutrients, Explain the Potential Be...

Explain the Potential Benefits of micro nutrients? The potential benefits of micro nutrients should also be taken into account when the nutrient allowances are defined for olde

Which alpha-helices would not be found in a protein, Please explain the dif...

Please explain the differences between an integral membrane protein, a Davison-Danielli peripheral membrane protein, and a protein in which alpha-helices would not be found.

What are the two main species of taenias, What are the two main species of ...

What are the two main species of taenias that cause human diseases? The two major species of taenias that cause disease in humans are Taenia solium, or the pork tapeworm, and T

What is an evolutionary explanatory hypothesis, Q. What is an evolutionary ...

Q. What is an evolutionary explanatory hypothesis for the secretion by the heart of a hormone that regulates the renal function? Which is that hormone? The renal regulator horm

Interventricular septum, It corresponds to the anterior and inferior interv...

It corresponds to the anterior and inferior interventricular grooves. Its right side is convex and bulges to the right ventricle. The septum has a posterior border which separates

When fecundation to be effective, Q. How long after ovulation must fecundat...

Q. How long after ovulation must fecundation occur to be effective? If fecundation doesn't occur around 24 hours after ovulation the released ovum often dies.

What are sensory receptors, What are sensory receptors? Sensory recepto...

What are sensory receptors? Sensory receptors are structures specialized in the acquiring of information, such as temperature, mechanical pressure, pH, chemical environment and

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd