Why the vast majority of segregation errors in human patient, Biology

Assignment Help:

Which of the following defines why the vast majority of segregation errors in human patients include the two sex chromosomes (XXY, XO, XYY) or chromosome 21 (triple 21)?

A. The centromeres of these three chromosomes lack attachment sites for spindle microtubules therefore leading to a higher than normal segregation error rate.

B. These three chromosomes have the highest probability to be mis-segregated during anaphase I and  II of meiosis.

C. Cells are more likely to survive with abnormal numbers of these three chromosomes whereas segregation errors of the other 20 human chromosomes are completely lethal.

D. Chromosome 21 as well as both sex chromosomes lack sequences that are recognized by proteins of the spindle assembly checkpoint (SAC). Thus the cell proceeds to anaphase even if these three chromosomes have failed to reach the metaphase plate.

 


Related Discussions:- Why the vast majority of segregation errors in human patient

How did gifford pinchot view nature, How did muir's impression of man's rel...

How did muir's impression of man's relationship with nature differ from Susan Fenimore coopers? And How did Gifford Pinchot view nature?

History of evolution, History of evolution? Evolution is usually define...

History of evolution? Evolution is usually defined as "change over time." In spite of the incredible diversity of life found on Earth, many fundamental characteristics are shar

Precautions for morphological characteristics of yeast cells, Precautions f...

Precautions for Morphological Characteristics of Yeast Cells? 1. Observe aseptic conditions. 2. Use only a small sample for staining. 3. No air bubbles should be in the s

Requirements of glutamine in diverticular disease, Q. Requirements of Gluta...

Q. Requirements of Glutamine in diverticular disease? Glutamine: Wile specific nutrients that may have an impact on diverticula disease have not been studied as thoroughly as t

Introduction to metabolism, Introduction to Metabolism An organism have...

Introduction to Metabolism An organism have to be managed its cellular organization and internal equilibrium despite the external forces which act upon it. Cells take in nutrie

Define about the gastric cancer, Define about the Gastric Cancer? Surgi...

Define about the Gastric Cancer? Surgical treatment is a very common mode of treatment in gastric cancer. Radiation and/or chemotherapy are given for patients with resected but

Atp, what is atp explain in detail?

what is atp explain in detail?

Nicotinic acid or niacin, Niacin affects all lipid parameters favorably. It...

Niacin affects all lipid parameters favorably. It is one of the only agents that reduces Lp (a) significantly (up to 30 per cent). Unfortunately, compliance is poor because of freq

Tunnel subvalvar stenosis, Tunnel Subvalvar Stenosis :  This variety ...

Tunnel Subvalvar Stenosis :  This variety is less common and extends from sub aortic area for a variable length of 10-30 mms (tunnel stenosis). In the severe variety, the tun

Benzene and ether non-polar or polar substances, Q. Are organic solvents li...

Q. Are organic solvents like benzene and ether non-polar or polar substances? the ethers and Benzene are molecules without electrically charged portions and thus they are non-p

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd