Why physiological cause of the syndrome called as cretinism, Biology

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Q. What is the physiological cause of the syndrome Called as cretinism?

Cretinism is caused by chronic deficiency of the thyroid hormones (T4and T3) during childhood. The chronic hypothyroidism during childhood may low stature and cause retardation due to the low basal metabolic rate in a period of life when development and growth of mind faculties occur.

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