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A substitution mutation occurs in the GRE making it unrecongnizable to the glucocorticoid receptor. What impact would this have on the transcription of the gene downstream of this element?
-reduced transcription downstream
-increase transcription downstream
-no change to transcription, increased translation
THYROID GLAND - It develops from the endoderm of the embryo. Th e thyroid gland is the largest endocrine gland located anterior to the thyroid cartilage of the larynx
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