What is the role of pharmacologic therapy in the treatment of peri implantitis.

Pharmacological therapy for patients presenting with an ailing implant involves subgingival irrigation for 10 days to 3 weeks (2 to 3 times per 24 hour time period). This may be completed at home following careful instructions from the clinician or dental hygienist. Chlorhexidine is most often prescribed because of its antimicrobial effect and substantivity at the affected site. Other pharmacological therapies include local applications of tetracycline fibers and systemic antibiotics.Bacteria associated with failing implants have been found to be sensitive to the following antibiotics: penicillin G, amoxicillin, combination of amoxicillin and metronidazole, and amoxicillin-clavulanate.