What is the inner life of the genome, Biology

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For the article entitled "The inner life of the genome" which of the following is true?

A. Individual chromosomes occupy explained territories within the nucleus.

B. The specific arrangement of chromosomes within the nucleus can vary between cell types, during various stages of development and during the onset of disease.

C. The position of chromosomes within the nucleus has an effect on whether individual genes are turned on or kept off.

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