What is the genetic disease in which this factor is absent, Biology

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What is factor VIII? What is the genetic disease in which this factor is absent?

Factor VIII has the function of activating factor X that in its turn is essential for the transformation of prothrombin into thrombin in the clotting cascade. Hemophilia A is the X-linked genetic disease in which the individual does not make factor VIII and so is more susceptible to severe hemorrhages.

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