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Which of the following results from the elimination of the sliding clamp?
A. DNA polymerase will no longer be processive and will fall off the double helix after synthesizing approximately 10-20 nucleotides.
B. Errors caused by replication slippage will enhance due to the inability of DNA polymerase to read by repetitive sequences of DNA.
C. Replication origins will not be deactivated thus replication will be initiated multiple times during a single cell cycle.
D. Nucleotides on the newly synthesized strand will fail to base pair correctly with the template strand.
Which factors are altered when cells are moved from an in vivo to an in vitro environment, and how do cells respond to these changes?
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