What is phenylketonuria, Biology

Assignment Help:

Q. What is Phenylketonuria?

The essential amino acid phenylketonuria is utilized for tissue protein synthesis and hydroxylated to form tyrosine. The hydroxylation reaction requires phenylalanine hydroxylase. Phenylketonuria (PKU) is a group of inherited disorders of phenylalanine metabolism caused by impaired phenylulanine hydroxylase activity. PKU cannot break down phenylalanine into another amino acid, tyrosine. Phenylalanine then builds up in the bloodstream and causes brain damage.

Phenylketonuria, commonly referred to as PKU, occurs at the age of 3 to 6 months and is characterized by developmental delay, microcephaly (abnormally small head), abnormal electro-encephalogram, eczema, musty odour and hyper activity. Lf untreated before three weeks of age, the metabolic imbalance produces irreversible mental retardation. The defect in metabolism in classic PKU is associated with less than 2% activity of normal phenylalanine hydroxylase.


Related Discussions:- What is phenylketonuria

Metamorphosis, Metamorphosis The phenomenon of metamorphosis is descri...

Metamorphosis The phenomenon of metamorphosis is described as a process during development which involves a remarkable change in morphology and physiology of the larva, so tha

Explain identifying features of rhizopus - food microbiology, Explain Ident...

Explain Identifying features of Rhizopus? Macroscopically Rhizopus appears as a white cottony mass (look at rhizopus growth on media above) growing rapidly and spread over enti

How does vitamin c act in the body, Q. How does vitamin C act in the body? ...

Q. How does vitamin C act in the body? What is the harm caused by insufficiency of vitamin C? Why was this deficiency also known as "sailors' disease"? Vitamin C, or ascorbic a

Which are the brain regions associated with memory, Which are the brain reg...

Which are the brain regions associated with memory? According to researchers some of the main regions of the nervous system associated with the memory phenomenon are the hippoc

Define osseointegration from diffrent points of view, Q. Define Osseointegr...

Q. Define Osseointegration from patients, microscopic and biomechanical points of view. a) From the view of the patient . An implant fixture is osseointegrated if it provid

Cilia and flagella – protozoans, Cilia and Flagella – Protozoans Cilia...

Cilia and Flagella – Protozoans Cilia and flagella basically have a similar structure and distinction between the two on structural basis does not exist. There is a filament o

Cracking, Cracking is the process in which large molecules are broken into ...

Cracking is the process in which large molecules are broken into smaller molecules.                      C 10 H 22         C 5 H 12 + C 5 H 10                      C 8 H

Explain the true indications of endodontic surgery, Explain the True indica...

Explain the True indications of Endodontic Surgery 1. Failure of non-surgical endo. Re-treatment "persistent lesion" 2. Failure of initial and retreatment will not achieve b

How public perception of science has distorted, Give an example of how the ...

Give an example of how the public perception of science has been distorted or manipulated to serve an alternative purpose.

Explain about iceberg phenomenon, Q. Explain about Iceberg Phenomenon? ...

Q. Explain about Iceberg Phenomenon? Phenomenon means a fact or occurrence that appears. Let us see how iceberg phenomenon is applied to Diabetes Mellitus (DM). Cases of dia

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd