What is phenylketonuria, Biology

Assignment Help:

Q. What is Phenylketonuria?

The essential amino acid phenylketonuria is utilized for tissue protein synthesis and hydroxylated to form tyrosine. The hydroxylation reaction requires phenylalanine hydroxylase. Phenylketonuria (PKU) is a group of inherited disorders of phenylalanine metabolism caused by impaired phenylulanine hydroxylase activity. PKU cannot break down phenylalanine into another amino acid, tyrosine. Phenylalanine then builds up in the bloodstream and causes brain damage.

Phenylketonuria, commonly referred to as PKU, occurs at the age of 3 to 6 months and is characterized by developmental delay, microcephaly (abnormally small head), abnormal electro-encephalogram, eczema, musty odour and hyper activity. Lf untreated before three weeks of age, the metabolic imbalance produces irreversible mental retardation. The defect in metabolism in classic PKU is associated with less than 2% activity of normal phenylalanine hydroxylase.


Related Discussions:- What is phenylketonuria

What is slime molds in diversity of life, What is Slime Molds in diversity ...

What is Slime Molds in diversity of life? Acrasiomycota and Myxomycota are appropriately named slime molds. They are slimy! The other part of their name comes from the time whe

Describe about the tertiary prevention - food allergy, Describe about the T...

Describe about the Tertiary Prevention - food allergy? The tertiary allergy prevention, as you already know, focus on patients with symptoms. Hence, the strategies will target

History of quantitative impacts on biology, Show History of Quantitative Im...

Show History of Quantitative Impacts on Biology Quantitative threads have been woven into the fabric of biology since at least the late 19th century, when Malthus warned of the

Cell, cells are the smallest structural units of the living matter and is ...

cells are the smallest structural units of the living matter and is capable of functioning independently.

What are the causes of constipation, Q. What are the Causes of constipation...

Q. What are the Causes of constipation? The most common causes of constipation are poor elimination habits, a lack of fibre in the diet, insufficient fluid intake, lack of exer

Solid waste management, Solid waste management, Other Management The solid...

Solid waste management, Other Management The solid wastes from a summer camp with 100 children and a staff of 25 are to be collected once per week. If bottles and cans (representi

Dissociative (conversion) disorders, DISSOCIATIVE  (CONVERSION) DISORDERS: ...

DISSOCIATIVE  (CONVERSION) DISORDERS: There is normally a considerable degree of conscious control over the memories and sensations that can be selected for immediate attentio

Explain the central dogma of molecular biology, Which one of the following ...

Which one of the following does not follow the central dogma of molecular biology? 1. Pea 2. Mucor 3. Chlamydomonas 4. HIV HIV is the central dogma of molecular bi

Define the process of dough formation, Define the process of Dough Formatio...

Define the process of Dough Formation? You already know that gluten is the protein found in wheat. A unique property of gluten proteins of wheat grain endosperm (and to a lesse

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd