What is phenylketonuria, Biology

Assignment Help:

Q. What is Phenylketonuria?

The essential amino acid phenylketonuria is utilized for tissue protein synthesis and hydroxylated to form tyrosine. The hydroxylation reaction requires phenylalanine hydroxylase. Phenylketonuria (PKU) is a group of inherited disorders of phenylalanine metabolism caused by impaired phenylulanine hydroxylase activity. PKU cannot break down phenylalanine into another amino acid, tyrosine. Phenylalanine then builds up in the bloodstream and causes brain damage.

Phenylketonuria, commonly referred to as PKU, occurs at the age of 3 to 6 months and is characterized by developmental delay, microcephaly (abnormally small head), abnormal electro-encephalogram, eczema, musty odour and hyper activity. Lf untreated before three weeks of age, the metabolic imbalance produces irreversible mental retardation. The defect in metabolism in classic PKU is associated with less than 2% activity of normal phenylalanine hydroxylase.


Related Discussions:- What is phenylketonuria

Explain the terms - sulphur and boron, Sulphur and Boron Boron is extra...

Sulphur and Boron Boron is extracted with hot water. Sulphur is extracted with 500 ppm solution of P solution (prepared from potassium dihydrogen orthophosphate or monocalcium

Explain food habits - diet presciption, Food Habits Food Habits: These ...

Food Habits Food Habits: These must be known  so that the diets  can  be  recommended keeping in mind the  food preferences  of  the patient. Whether a person is  a vegetarian

Write in 3-4 lines about the term belief, Q. Write in 3-4 lines about the t...

Q. Write in 3-4 lines about the term belief? Beliefs are learned by us when we were young. These include religious beliefs and beliefs about behaviour. Some beliefs lead to hea

Cytology, Cytology: The study of form or culture including the behavior of ...

Cytology: The study of form or culture including the behavior of nucleus and other organelles is called cytology. Cytology means "the study of cells". Cytology is the branch of lif

Aleurone grains, ALEURONE GRAINS - Also known as Plant lysosome , beca...

ALEURONE GRAINS - Also known as Plant lysosome , because they contain hydrolytic enzymes. Consists of Proteins. They are also known as Aleuroplast because they are ric

Excretion in cockroach, EXCRETIO N IN COCKROACH- Animal is uricotelic....

EXCRETIO N IN COCKROACH- Animal is uricotelic. Excretory organs are malphighian tubules. 60-150 in 6-8 groups. In each group 10-15. Yellow coloured, blind tube, open in gut

Organs in animal - excretion, Normal 0 false false false ...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Surgical treatment of infective endocarditis, Cardiac surgical intervention...

Cardiac surgical intervention has an increasingly important role in the treatment of intracardiac complications of endocarditis. Retrospective data suggest that mortality is unacce

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd