What is phenylketonuria, Biology

Assignment Help:

Q. What is Phenylketonuria?

The essential amino acid phenylketonuria is utilized for tissue protein synthesis and hydroxylated to form tyrosine. The hydroxylation reaction requires phenylalanine hydroxylase. Phenylketonuria (PKU) is a group of inherited disorders of phenylalanine metabolism caused by impaired phenylulanine hydroxylase activity. PKU cannot break down phenylalanine into another amino acid, tyrosine. Phenylalanine then builds up in the bloodstream and causes brain damage.

Phenylketonuria, commonly referred to as PKU, occurs at the age of 3 to 6 months and is characterized by developmental delay, microcephaly (abnormally small head), abnormal electro-encephalogram, eczema, musty odour and hyper activity. Lf untreated before three weeks of age, the metabolic imbalance produces irreversible mental retardation. The defect in metabolism in classic PKU is associated with less than 2% activity of normal phenylalanine hydroxylase.


Related Discussions:- What is phenylketonuria

Explain whey protein concentrates, Whey Protein Concentrates You alrea...

Whey Protein Concentrates You already know that whey is the residual liquid substance that is obtained by separating the coagulum from milk during cheese making. There are imp

Autotomy and regeneration, Autotomy and Regeneration Shedding of body...

Autotomy and Regeneration Shedding of body parts in self-defense to avert the attention of the predator-enemy or in any other emergency is a type of autotomy (auto: self, tom

Blastula, Blastula is the ball of cells surrounding a fluid-filled cavity ...

Blastula is the ball of cells surrounding a fluid-filled cavity (known as blastocoel) which is produced by the cleavage of a zygote.

Reproduction, Normal 0 false false false EN-IN X-NONE...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Two dimensional gene scanning method, Two dimension gene scanning technique...

Two dimension gene scanning technique is a high resolution system for finding of mutational variants in multiple genes. This method is on the basis of combination of extensive poly

Why the rate of photosynthesis does increases, Why the rate of photosynthes...

Why the rate of photosynthesis does increases, peak, and then reduces as temperature increases? Increasing the temperature initially accelerates the many chemical reactions in

Determine the process of rna editing, Which of the following is a true stat...

Which of the following is a true statement regarding the process of RNA editing? A. RNA editing alters the sequence of the mRNA message thereby permitting for an enhance in pro

How molecular biology change forsenic biology, Explain in 100+ words Why/ho...

Explain in 100+ words Why/how did molecular biology change forsenic biology.

Explain the prokaryotic and eukaryotic core promoters, Which of the followi...

Which of the following is a false statement regarding prokaryotic and eukaryotic core promoters? A. The core promoters of eukaryotic genes have more recognition elements for ge

Mixed tricuspid stenosis and regurgitation , Mixed Tricuspid Stenosis and R...

Mixed Tricuspid Stenosis and Regurgitation:  Rheumatic involvement of the tricuspid valve is often seen in association with involvement of mitral and rarely aortic valve. Isolated

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd