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What is osteoblast
The osteoblast is the key for the development of new bone. It is essential that a large number of osteoblasts accumulate on the implant surface(contact osteogenesis). This process is called as Osteoblast recruitment. These cells are derived from the mesenchymal stem cells, the inner cell rich layer of the periosteum and the endosteum. Although systemic factors like hormones, ion concentration play a role in this process of recruitment, it is the local factors which are critical. It is signalling to precursor cells by the cytokines. Also bone morphogenic proteins which represent the osteoinductive proteins of bone are critical in this process of recruitment
Nitrate Uptake Nitrate must enter the cells before undergoing assimilatory reduction by the joint action of nitrate reductase and nitrite reductase. Cells accumulate NO - 3
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