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What is Oogenesis ?
The female sex cells, or eggs, are formed in the ovaries, the primary sex organs of the female. The precursor of the egg cells, or oogonia, are formed during the prenatal development of the ovaries in the female embryo. However, the oogonia do not increase in number until after the third month of fetal development.
Oogonia divide by mitosis to form primary oocytes. These cells gradually die off, but about 200,000 are left in each ovary at puberty (about 11 to 14 years of age). Over the course of a woman's reproductive life, only about 450 oocytes will mature completely into eggs.
The primary oocyte begins meiosis, undergoing a very unequal division in which the larger cell becomes a secondary oocyte, and the other forms the first polar body, which eventually dies off. The second meiotic division, also unequal, forms a haploid ootid and a second polar body that also dies off. What is left is a single haploid egg cell or ovum (plural ova) that is 75,000 times larger than a sperm cell. The ovum contains contains proteins, lipids, and other raw materials for development. It is thought that the reason 3 of the 4 cells that result from meiosis die off is to provide the one surviving egg with sufficient resources for development.
Biopathways 1. Find out pathway information about these proteins using the Human Reactome. O00327 O14503 O75586 O95096 P01137 P01308 P06744 P08240 P12
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