What is malabsorption syndrome, Biology

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Q. What is Malabsorption Syndrome?

Did you know that a major part of the absorption of nutrients takes place in the small intestine and the set of enzymes involved in this process are called disaccharidases. In some conditions either genetically, or due to some intestinal damage there appears to be a deficiency of some of these enzymes, which in turn, leads to the malabsorption of some of the nutrients precipitating symptoms of diarrhoea, dissention and abdominal discomfort and steatorrhoea (fat in stools).

These conditions are together referred to as Malabsorption Syndromes. The term 'malabsorption syndrome', as you have learnt earlier also, is used to describe deficient absorption to a variable degree of a number of substances such as fats, proteins, carbohydrates, vitamins, minerals and water.

Before we understand about this syndrome, let us look at the following case study. Anuradha, a teenager, presents to the physician's office with a two-year history of intermittent diarrhoea. Her reports reveal a past history of anaemia, anorexia and minor abdominal pain. Her weight has been the same for two years now. Her mother has attributed this to her having n "rough time in school". Her mother also questions whether the symptoms could be related to a recent move from their home. She has not yet reached menarche; A diet history suggests a normal diet with adequate iron intake. Can you guess what she suffers from and what could be the causative factors leading to such a condition?


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