What is isoniazid, Biology

Assignment Help:

Isoniazid 

Serum aminotransferase activity increases in 10% to 20% of patients taking isoniazid, especially in the early weeks of treatment, but often returns to normal even when the drug is continued. Severe liver damage due to isoniazid is less common than previously thought. It is more likely to occur in patients more than 35 years old, but can also occur in younger patients. Routine monitoring is not necessary except for patients with pre-existing liver disease. Medical Letter consultants recommend stopping isoniazid when serum aspartate amino transferase activity reaches five times the upper limit of normal or if the patient has symptoms of hepatitis, but it can sometimes be re-started later.

Peripheral neuropathy occurs rarely and can usually be prevented by supplementation with pyridoxine (Vitamin B6, 10-25 mg/day), which is recommended for patients with chronic alcohol use, diabetes, chronic renal failure or HIV infection, and for those who are pregnant, breast feeding or malnourished.

 


Related Discussions:- What is isoniazid

Non - pharmacological management, Great importance is being given to life s...

Great importance is being given to life style modifications because of definite benefits observed in patients who follow this. Life style changes have advantages not only in the co

What is the significance of pharyngeal gill slit, What is the significance ...

What is the significance of Pharyngeal gill slit ? Lateral opening in the wall of the pharynx which allows water to enter into the mouth and exit through the pharynx. This is on

Gaand marao, Ask questionfjhfkdf g g fg fgfgh h gh h #Minimum 100 words ac...

Ask questionfjhfkdf g g fg fgfgh h gh h #Minimum 100 words accepted#

Which of structures is the nuclear membrane composed, Q. which of structure...

Q. which of structures is the nuclear membrane composed? Eukaryotic cells have nucleus delimited with two juxtaposed membranes that continue with the membrane of the endoplasmi

Explain the mechanism of enzyme action, Question 1 Give an account of t...

Question 1 Give an account of t-RNA 2 Write short note on Competitive inhibition 3 What are ketone bodies? Write the mechanism of ketogenesis 4 Describe the properties of nucle

Explain leaf silhouettes, Leaf silhouettes Place a leaf on a sheet of w...

Leaf silhouettes Place a leaf on a sheet of white paper and hold it securely with thumb or finger. Press a piece of natural or artificial sponge next to an ink pad. With short,

Define factors affecting microbial survival and growth, Define Factors Affe...

Define Factors Affecting Microbial Survival and Growth? Microbes commonly present on the food, we have seen, include members of the genera Bacillus, Clostridium, Pseudomonas, S

Explain the steps of converting food into energy, Explain the steps of conv...

Explain the steps of converting food into energy. There are four steps to convert food into energy: a) Ingestion, mastication and swallowing : Ingestion or taking in of food

Cardiac resynchronization therapy, This innovative, pacemaker-based approac...

This innovative, pacemaker-based approach to the treatment of patients with heart failure who have a wide QRS complex (>140 ms) on 12-lead ECG aims at providing electromechanical c

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd