Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
What is Iron Overload and Toxicity?
We have seen that absorption of iron is very effectively regulated. This prevents overload of the tissues with iron from diet/supplements in normal healthy individuals. However, an excessive body burden of iron can be produced by greater-than-normal absorption from the alimentary canal, by parenteral injection or by a combination of both. For instance, people with genetic defects develop iron overload as it occurs in idiopathic haemochromatosis. It is a hereditary disorder of iron metabolism characterized by abnormally high iron absorption owing to a failure of the iron absorption control mechanism at the intestinal level.
High deposits of iron in the liver and the heart can lead to cirrhosis, hepatocellular cancer, congestive heart failure and eventual death. African or Bantu siderosis, chronic liver disease, pancreatic insufficiency, shunt haemochromatosis and certain types of refractory anaemia have been found to be associated with iron overload. It has recently been shown that excess iron intake via overuse of iron supplements could pose a possible health risk. Cellular and tissue injury due to free radical reactions appears to be the possible mechanism. Normally iron is bound tightly to the proteins. However, it is possible that excess iron intake permits some iron to be in a free form. Associated complications may include increased risk for bacterial infection, neoplasia, arthopathy, cardiomyopathy and endocrine dysfunction.
what is the classification of vertibrates
Explain Acidic Stains (anionic) - Types of Stains? These are sodium, potassium, calcium or ammonium salts of coloured acids, which on ionization give negatively charged chromog
Describe Pathophysiology of tetralogy of fallots ? The PS causes concentric hypertrophy of right ventricle without enlargement. The right ventricular pressure are equal to or h
Caffeine and alcohol both block the secretion of ADH from the posterior pituitary gland. Explain what this does to fluid balance. Does it make sense to drink caffeine before an ath
Why can it be said that each glucose molecule runs the Krebs cycle twice? Every glucose molecule "cycles" the Krebs cycle twice because after glycolysis each used glucose has g
Ask questiona brief assignment on it #Minimum 100 words accepted#
Explain about Bone lining cells Bone lining cells are basically inactive osteoblasts (in terms of making bone) that line bone surfaces. Osteocytes are osteoblasts that have be
Discuss the refractive and response to wound functions of cornea. Refractive Function: Cornea, through its interaction with the tear film, forms a smooth refractive functi
Which of the following assist in the digestion of fats? A. Production of bile salts in the liver and the secretion of those bile salts into the small intestine. B. Emulsific
Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd