Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Q. What is Galactosemia?
Galactosemia is a genetic disorder caused by deficient functioning of any of these three enzymes namely galactokinase, galactose -1 - phosphate uridyl transferase, or UDP galactose - 4- epimerase. Galactose derived from the hydrolysis of lactose in the intestine is absorbed normally. Bur in the absence of gal-1-P-transferase it leads to the accumulation of galactose, galactose-1-phosphate, and galactitol in the blood and tissues. Accumulation of gal-1-P reduces the intracellular phosphate for high energy phosphate bonds. Thus ATP, GTP and CTP are reduced.
Patients with galactokinase deficiency suffer only from cataract; Galactitol accumulates in the lens of the eye creating an osmotic gradient that allows the glutathione from the lens to efflux. Due to this the concentration of glutathione in the lens is decreased. Glutathione peroxidase and hydrogen peroxidase are inactivated. As a result hydrogen peroxide accumulates in the lens denaturing the proteins of the lens. This leads to the production of lenticular cataracts.
Explain Effect of Nutrient Supplements on Drugs? A nutrient or nutrient supplement can alter the pharmacological action of a drug by enhancing the drug effect or by opposing it
What is the function of the skin in humans? The skin is the external covering of the body. In humans its major functions are protection, perception of information from the envi
What is the difference between the lateral and the apical buds of the plants? Lateral buds are portions of meristematic tissue situated in the base of the shoots. Apical bud
Carbomedics Valve : Almost similar to StJude Medical valve, his is a low profile bileaflet valve made of pyrolitic carbon. On echo cardiography four small jets of regurg
Define Life Cycle of Spore Forming Bacteria? One endospore is formed per bacterial cell. The process of formation of endospore is called sporulation that occurs in an organized
Define Drug effects on Metabolism of dietary components? Drugs can also compete with, or inhibit, the metabolic conversion of some micronutrients to their active metabolites,
How many g of glucose will be required to make 750 ml of a 0.5% w/v solution? Please show all steps.
What is Erythropoietin (EPO) A. is secreted by peritubular interstitial cells of the kidney cortex. B. acts by increasing the production of red blood cells by cells in
The two gases making highest relative contribution to the greenhouse gases are: 1. CO2 and CH4 2. CH4 and N2O 3. CFC55 and N2O 4. CO2 and N2O CO2 and CH4
Q. Classifications of mechanical cleaning devices? In general, three classifications of mechanical cleaning devices are available for the dental office. They are: ult
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd