Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Q. What is Galactosemia?
Galactosemia is a genetic disorder caused by deficient functioning of any of these three enzymes namely galactokinase, galactose -1 - phosphate uridyl transferase, or UDP galactose - 4- epimerase. Galactose derived from the hydrolysis of lactose in the intestine is absorbed normally. Bur in the absence of gal-1-P-transferase it leads to the accumulation of galactose, galactose-1-phosphate, and galactitol in the blood and tissues. Accumulation of gal-1-P reduces the intracellular phosphate for high energy phosphate bonds. Thus ATP, GTP and CTP are reduced.
Patients with galactokinase deficiency suffer only from cataract; Galactitol accumulates in the lens of the eye creating an osmotic gradient that allows the glutathione from the lens to efflux. Due to this the concentration of glutathione in the lens is decreased. Glutathione peroxidase and hydrogen peroxidase are inactivated. As a result hydrogen peroxide accumulates in the lens denaturing the proteins of the lens. This leads to the production of lenticular cataracts.
Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4
How Primarily Energy Deficiency cause PEM? Surveys on preschool children in different parts of the country reveal that PEM is primarily due to dietary energy deficiency arising
What is digestion? The ingested food material is broken down into smaller constituents which are assimilable by the blood. The process through which the major nutr
Signify Asexual and how it is formed? Organisms which do not reproduce by recombination of genetic material contained in gametes. There is not any combination of a haploid sper
are protozoans primitive to life .
Secondary Succession - Community Change Secondary succession is the sequential development of biotic communities after the complete or partial destruction of the existing comm
The cytosolic surface of the erythrocyte plasma membrane is covered through a network of peripheral membrane proteins which make up the cytoskeleton in the figure. The
Explain the Minimum Requirement of nutritional needs? Minimum nutrient requirement is defined as the 'lowest amount of the nutrient ji-om the diet that will prevent clinically
Explain the Skeletal System? Skeletal System: The support framework, or skeleton, in the human body is composed of mostly hard mineral substances. Unlike crustaceans or insec
Which are the plant tissues that form the plant roots? The roots have a central portion known as medulla made of vascular tissue (inner xylem and outer phloem). The medulla is
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +1-415-670-9521
Phone: +1-415-670-9521
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd