Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Q. What is Galactosemia?
Galactosemia is a genetic disorder caused by deficient functioning of any of these three enzymes namely galactokinase, galactose -1 - phosphate uridyl transferase, or UDP galactose - 4- epimerase. Galactose derived from the hydrolysis of lactose in the intestine is absorbed normally. Bur in the absence of gal-1-P-transferase it leads to the accumulation of galactose, galactose-1-phosphate, and galactitol in the blood and tissues. Accumulation of gal-1-P reduces the intracellular phosphate for high energy phosphate bonds. Thus ATP, GTP and CTP are reduced.
Patients with galactokinase deficiency suffer only from cataract; Galactitol accumulates in the lens of the eye creating an osmotic gradient that allows the glutathione from the lens to efflux. Due to this the concentration of glutathione in the lens is decreased. Glutathione peroxidase and hydrogen peroxidase are inactivated. As a result hydrogen peroxide accumulates in the lens denaturing the proteins of the lens. This leads to the production of lenticular cataracts.
Explain about the Transcellular Route - Calcium? Transcellular Route: It operates primarily in the duodenum and proximal jejunum. It is stimulated when Ca ingestion is lower re
GENE INTERACTIONS (POST MENDELIAN GENETICS) Phenotypic expression of a gene may be altered by the influence of other genes. The modification of the normal phenotype of certain
what major nerve do you think is being compressed when a person often feel pain in the posterior surface of the thigh radiating to the area behind the knee and where is the likely
Q. Planning of diabetes counselling? You have helped the client to find out various solutions to a problem and understand the coping skills, ensured support from the family su
You have a 1M KCl stock solution and a 85 mg/ml sulphuric acid stock solution. How will you make a 200 ml single solution containing 20mM KCl and 18 mg/ml sulphuric acid?
It involves the standardization of copper sulphate solution. This is same as done in the previous activity. 1) Pipette accurately 5 ml of Solution A and Solution B in conical f
Ventricular Septal Defect (VSD) In ventricular septal defect there is abnormal communication between right and left ventricle. Anatomically 90 per cent of all VSD are located
Q. Can the amount of available energy in a given trophic level be larger than the available energy in inferior trophic levels? What does that condition means to the conformation of
Classification of Enzymes : Enzymes are classified into the following six main categories in according with the nature of reaction the catalyze: 1. Oxidoreductases
Ask question end product of aerobic repiration are
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd