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What is frog central nervous system
Consider Neuron B in the frog central nervous system whose plasma membrane has a newly discovered ligand-gated ionotropic receptor, named the LGD receptor. The channel in the same molecular complex as the LGD receptor is termed the LGD receptor channel and is a monovalent cation channel that, when open, is permeable to both sodium and potassium. The Nernst equilibrium potential for sodium in Neuron B is +60 mV, and the Nernst equilibrium potential for potassium in Neuron B is -90 mV. The threshold for an action potential in Neuron B is -55 mV and the resting potential for Neuron B is -70 mV. LGD is an agonist for the ligand-gated ionotropic receptor. When LGD binds to its binding site, there is an increase in conductance of both sodium and potassium in the LGD receptor channel. Neuron A synapses onto Neuron B. Neuron A's transmitter is LGD.
A. When the LGD receptor channel is open in Neuron B, its potassium conductance equals its sodium conductance. In response to an action potential in Neuron A, then there will be an excitatory postsynaptic potential in Neuron B.
B. When the LGD receptor channel is open in Neuron B, its potassium conductance equals four times its sodium conductance. In response to an action potential in Neuron A, then there will be a voltage increase and an action potential in Neuron B.
C. When the LGD receptor channel is open in Neuron B, its potassium conductance equals nine times its sodium conductance. In response to an action potential in Neuron A, then there will be an inhibitory postsynaptic potential in Neuron B.
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