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While various positive control components lie close to the gene they regulate additional can be situated long distances away (sometimes 10-50 kb) either upstream or downstream of the gene shown in the figure. A long-distance positive control series of this type is called as an enhancer if the transcription factor(s) which binds to it enhances the rate of transcription. An enhancer is classically 100-200 bp long and haves several sequence elements which act together to give the whole enhancer activity. When they were first found, enhancers were viewed as a distinct class of control component in which they:
? Over long distances can activate transcription;
? It can be located downstream or upstream of the gene being controlled;
? Are active in moreover orientation with respect to the gene.
Explain the Appearance of the Pupil The pupil should appear round and regular. The normal diameter is 2-4 mm. On stimulation by light, the pupil constricts, so as to redu
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State three ways in which the absorbing surface of the small intestine is increased. The absorbing surface of the small intestine is increased by:- (a) being very long
Define Objectives to know about methods of food processing? After studying this unit, you will be able to: Enumerate the different methods of food processing Enlist
How are buffers significant to the functioning of living systems? By neutralizing small amounts of acid or base that might be added to a solution, buffers keep pH values at nor
how can explain
Pyruvate kinase catalyzes the third irreversible move in glycolysis. It is activated by fructose 1, 6-bisphosphate. The ATP and amino acid alanine allosterically inhibit the enzy
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Preparation of the standard curve for haemoglobin? Label 6 clean dry rest tubes and label them as S1 -S6 Add 5 ml of Drabkin's solution to test tube numbers S2 - S6
Diabetic foot are impaired blood supply to foot Diabetic foot are impaired blood supply to foot i.e. vasculopathy. This leads to ischaemia which in turn leads to delayed or non
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