Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
What is Dyslipidaemia ?
The results of epidemiological studies, as well as trials with angiographic or clinical endpoints, confirm the importance of various lipid fractions in the pathogenesis of atherosclerosis. There is a strong and graded positive association between total and LDL cholesterol and risk of vascular events (mainly ischaemic heart disease) extending over a wide range of cholesterol concentrations. This association applies to individuals with or without established CAD as well as to women and men. Other risk factors can substantially aggravate the effects of LDL cholesterol.
The other fraction of the lipid is HDL cholesterol. It is also called 'good' cholesterol as there is a strong and inverse association between HDL cholesterol and the risk of CAD in both men and women and in subjects with or without established CAD; the lower the concentration of HDL-cholesterol the greater the risk of CAD. The inverse association between HDL-cholesterol levels and CAD risk at least equals the positive association between CAD risk and serum LDL cholesterol events. There is now evidence from the Veterans Administration High density Lipoprotein Cholesterol Intervention Study (VA-HIT) that the increase in HDL-cholesterol in CAD patients is followed by a significant decrease in major coronary events.
Triglycerides are the other lipid components in the blood 2nd they also contribute to an increased risk of coronary artery disease by a number of mechanisms. The triglyceride rich lipoproteins may be independently atherogenic or they may promote atherosclerosis by inducing a procoagulant state and promoting thrombosis.
While level of individual lipid factor may be important in the pathogenesis of coronary atheroclerosis, interplay of different lipid fractions is much more significant. For example, at a given level of LDL cholesterol, the atherogenic potential is enhanced in presence of low HDL cholesterol level. Again, the ratio of total cholesterol (TC) to HDL cholesterol (HDLc) emerges as the most powerful predictor of atherosclerosis; a TC/HDLc ratio more than 4,5 is associated with high risk of CAD.
Closed Mitral Valvotomy : This has been 1-eplaced by balloon mitral valvotomy (BMV) in most centres. It is done in cases of either pure mitral stenosis or with .triv
How many ATP molecules are made after glycolysis? Glycolysis is a process same to glucose degradation in fermentation. It forms (final balance) two molecules of ATP for each br
Note on production of haploid by tissue culture.
Define Fluconazole It is a weaker inhibitor of CYP3A4 than itraconazole or ketoconazole but may still increase serum concentrations of drugs metabolized by 3A4, like cyclospor
Explain chemical bonds in basic chemistry? Chemical Bonds : Chemical bonds are forces that join atoms together in a functional unit. There are three types of bonds that can
Define the Ascorbic Acid - Basic Concepts? Ascorbic acid is a water-soluble vitamin, whose structure is shown in Figure. You would have noticed that its structure resembles glu
Defone Economic consequences of malnutrition? Figure explains the economic consequences of malnutrition. You would note from the Figure that the economic productivity of the in
Ultrasonography: Ultrasounds are sound waves with a frequency of higher than the upper range of human hearing i.e., approximately 20,000 cycles per second (20 kilohertz).
Insulin was the first protein to be sequenced biochemically. Assuming that there were no introns involved in the process, what are the possible DNA sequences that produced the last
What is Excessive Fat Intake? Although minimum amount of fat is essential as calculated above but upper limit of fat should be drawn due to its link with an increased risk of d
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd