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What is bicuspid aortic?
Bicuspid aortic valve is the most common form of CHD seen in adults. Isolated bicuspid aortic valves may be stenotic or non-stenotic to start with. The non-stenotic BCAV may remain functionally normal throughout a normal life span to start with. It may become stenotic through fibrocalcific thiclcening or may become regurgitant.
Aortic regurgitation may occur either spontaneously or alter an episode of infective endocarditis.
Augmentation Therapy: The functional gene is introduced in addition to the defective gene endogeneous to the cell(s) in this somatic cell gene therapy, i.e. the improved cell
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