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Zymogens, or proenzymes, are enzymes secreted in inactive form. Under certain conditions, a zymogen shifts to the active form of the enzyme. Zymogen secretions in general occur due to the enzyme activity can harm the secretory tissue.
For example, the pepsinogen secreted by the stomach becomes active under acid pH turning into the enzyme pepsin. Other well-known zymogens are trypsinogen and chymotrypsinogen. Enzymes are secreted by the exocrine pancreas and correspondingly trypsin and chymotrypsin.
If the condition or the post disease as a result of intraradicular infection----> treated conventionally via apex " non-surgical ", ---->Here we have 2 options either coronal
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Double Vessel Disease (DVD) : Percutaneous intervention with stetting is usually advised for these patients. However if it is left main equivalent disease or when block is close
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