Ventricular septal defect (vsd), Biology

Assignment Help:

Ventricular Septal Defect (VSD) 

In ventricular septal defect there is abnormal communication between right and left ventricle. Anatomically 90 per cent of all VSD are located in  the membranous part of  the ventricular septum with a variable extension into adjoining muscular part of  the ventricular septum. Ventricular septal defect is the most common congenital cardiac lesion.  

Pathophysiology and Hemodynamics 

In ventricular septal defect there is shunting of  oxygenated blood from the left to the right ventricle as the pressure in the left ventricle is higher than in the right ventricle. This results in passage of oxygenated blood in greater amounts from left to the right ventricle, leading to pulmonary hypertension. In extreme cases there may be only one ventricle. The muscles, hypertrophy, because of  increased pressure in the right ventricle due to left to right shunt and pulmonary resistance. The muscles of  right atrium also enlarge due  to increased pressure. If pulmonary vascular resistance increases, the left to right shunt gets reduced, resulting in right to left shunt. Unoxygenated blood then crosses to the left ventricle and enters the systemic circulation. This phenomenon is known as Eisenmenger syndrome, a combination of pulmonary hypertension with reversed shunting.  


Related Discussions:- Ventricular septal defect (vsd)

Other complications of prosthetic valves, Other Complications of Prosthetic...

Other Complications of Prosthetic Valves :  One of the dreaded complications of mitral valve replacement is ventricular rupture. It is difficult to manage and so it is better avoi

ANAT 260 Signature Assignment, ANAT 260 Signature Assignment Instructions: ...

ANAT 260 Signature Assignment Instructions: Address each question below as it relates to the case study given. A patient was brought to the Emergency Department by ambulance with t

Biology, what is the relationship between an infection and spleen

what is the relationship between an infection and spleen

Amoebae - protozoan, Amoebae - Protozoan Amoebae may be naked or enclo...

Amoebae - Protozoan Amoebae may be naked or enclosed in tests or shells. The marine, freshwater and parasitic naked amoebae have large commonly tubular lobopodia or fine strap

Explain first meiotic division, Q. What are the periods of the first meioti...

Q. What are the periods of the first meiotic division? Meiosis I is divided into metaphase I, prophase I, anaphase I and telophase I.

Explain unacceptable aesthetics, Unacceptable Aesthetics The implant wh...

Unacceptable Aesthetics The implant which has successfully integrated with bone may still be a failure if the Prosthesis which it is designed to support does not meet with the

Explain antibacterial activity, Antibacterial activity   Rifaximin reach...

Antibacterial activity   Rifaximin reaches high concentrations in the intestinal tract and is active in vitro against a broad range of enteropathogens, including ETEC, EAEC, Shi

State the term in detail hydrostatic skeleton., State the term in detail hy...

State the term in detail hydrostatic skeleton. Formed from a fluid-filled and closed cavity surrounded by a body wall comprising muscles oriented in different directions. Muscu

Determine the alpha-islet cells of the pancreas, Determine the alpha-islet ...

Determine the alpha-islet cells of the pancreas. Person X is a healthy human who has volunteered to take experimental drug Y.  Person X has a normal dinner at 6 PM on April 1 a

Cell, what is cell and what are the components of cell

what is cell and what are the components of cell

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd