Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
In developing countries because of poor compliance, poverty, ignorance, primary and secondary prevention strategies are difficult to implement properly. Also in western countries (USA), where there is resurgence of ARF, interest in vaccine development has appeared. However, there are quite a few technical problems in development of vaccines. There are 2 types of vaccines.
I) Vaccines Against Virulence Factors Conserved Amongst Various GAS Despite antibodies to these conserved antigens, people are affected by multiple serotypes of GAS. Hence there remains a doubt regarding the protective efficacy of antibodies against GAS infections.
II) Vaccines Based on Type Specific, Hypervariable N-terminal Regions of M Proteins Life long immunity which is protective (25 to 30 years after infection) is achieved by antibodies against the hypervariable N-terminal of M-Protein. Considering this fact, using recombinant DNA technology, synthetic peptide copies of the hypervariable N-terminal of the M-protein are being manufactured. These synthetic peptides produce only bacterial antibodies without host cross-reactive antibodies. Currently N-terminal synthetic peptides of multiple serotypes of GAS are linked to a carrier protein to produce opsonizing antibodies. Tetra, hexa and octavalent vaccines incorporating M 1, 2, 3, 5, 6, 18, 19 and 24 N-terminal peptides are being evaluated in animals.
Explain the term - Muscle Contraction Headache This is one of the most common headaches. It is also known as tension or nervous headaches. They result from sustained contractio
cassification of mode of nutrition
Other Psychiatric Emergencies: 1) Psychotropic Drug Withdrawal Abrupt cessation of antipsychotic, benzodiazepines result in symptoms of withdrawal including abdominal pain, i
Zinc (Zn) - Micronutrients In its function in some enzyme systems, zn 2+ resembles Mn 2+ in that it brings about substrate binding and conformational changes in enzymes. A n
Explain the Radiographic Failure of Root Canal Treatment It is the persistence or development of pathosis radiographically. Specifically, this is a radiolucent lesion that has
2. Vaccinations against various childhood diseases have contributed to the entry of women, particularly mothers, into the fulltime workplace. a. Is this statement supported by data
Anaerobic Oxidation Embden Meyerhof pathway The initial stage of biological oxidiation includes a series of nine main sequential steps of reactions known as Embd
Consider Neuron B in the frog central nervous system whose plasma membrane has a previously unknown channel that is selectively conductive to a newly discovered tetravalent anion n
The gaseous pollutants can be controlled through the techniques of combustion, absorption adsorption and cold trapping. (a) Combustion: Though combustion is a major cause of i
Q. What are the major functions of the bacterial flora within the human gut? Bacteria that live inside the gut have great importance in digestion. Several polysaccharides like
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +1-415-670-9521
Phone: +1-415-670-9521
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd