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The various types and their description of Heart failure are as follows:
Left Sided Versus Right Sided Heart Failure
Predominantly left sided failure is seen in left ventricular infarction, hypertension, aortic and mitral valve diseases. The symptoms are due to pulmonary congestion (backward failure) and manifest as various degrees of dyspnoea to acute pulmonary edema. Fatigue, muscle weakness and mental confusion may also be seen as a result of forward failure.
The commonest cause of right-sided failure is left-sided failure, but is also seen in pulmonary hypertension due to other causes. Raised jugular venous pressure, hepatic congestion and edema are classical features of right-sided failure.
A substitution mutation occurs in the GRE making it unrecongnizable to the glucocorticoid receptor. What impact would this have on the transcription of the gene downstream of this
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