Tumor suppressor genes, Biology

Assignment Help:

Tumor Suppressor Genes

Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-


Related Discussions:- Tumor suppressor genes

Typological species concept, The typological species concept was suggested ...

The typological species concept was suggested by Plato more than 2000 years ago. According to this concept, the immense variety in nature can be reduced to a few "types". Individua

Cockroach heart, How last chamber of heart in cockroach receives blood with...

How last chamber of heart in cockroach receives blood without having ostia?

Define basic working of the endocrine system, Q. How does the circulatory s...

Q. How does the circulatory system participate in the functioning of the endocrine system? The circulatory system is basic for the functioning of the endocrine system and the b

What are gibberellins, What are gibberellins? Where are they produced? ...

What are gibberellins? Where are they produced? Gibberellins are plant hormones that stimulate plant growth, flowering and fruit formation (also parthenocarpy) and the germina

Explain about the food spoilage, Explain about the Food Spoilage? Foods...

Explain about the Food Spoilage? Foods gradually undergo deterioration or spoilage from the time they are harvested, caught, slaughtered or manufactured. Therefore, delay in th

Explain phenotypical characteristics of alleles of a gene, What are few exa...

What are few examples of phenotypical characteristics that present two or more varieties and of phenotypical features that do not vary? In relation to the genes correspondent to th

Types of polysaccharides on the basis of functionality, FUNCTIONAL L Y PO...

FUNCTIONAL L Y POLYSACCHARIDES ARE OF THREE TYPES - Storage, Structural, Mucopolysaccharides Storag e polysaccharides function as reserve food which can be hydrolyzed

State the branemark theory of osseointegration, Branemark's Theory of Osseo...

Branemark's Theory of Osseointegration In 1952, Swedish orthopedic surgeon, Branemark, conducted microscopic studies done in situ of the bone marrow in rabbit's fibula with in

Clostridium perfringens infections, Clostridium perfringens infections ...

Clostridium perfringens infections Cl. perfringens is a rod-shaped, spore-bearing anaerobic organism. It is capsulated and non-motile. A characteristic feature of the organism

Groups of living beings that form the protist kingdom, Q. Which are the gro...

Q. Which are the groups of living beings that form the protist kingdom? The protist kingdom includes algae and protozoans. (Two groups of fungi with similar characteristics to

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd