Tumor suppressor genes, Biology

Assignment Help:

Tumor Suppressor Genes

Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-


Related Discussions:- Tumor suppressor genes

Classification of carbohydrates - degree of polymerization, Define Classifi...

Define Classification of Carbohydrates - Degree of Polymerization? Classification on the basis of Degree of Polymerization (DP) Carbohydrates are classified by their degree

Explain the urinary system in human body, Explain the Urinary System in hum...

Explain the Urinary System in human body? The urinary system removes the waste materials produced as a result of all the metabolic process required to sustain life. The process

What are the oligosaccharides and monosaccharides, Q. What are the oligosac...

Q. What are the oligosaccharides, monosaccharides and polysaccharides? Monosaccharides are simple molecules of carbohydrates that cannot be broken down into smaller molecules o

Explain the management of middle - third perforation, Explain the Managemen...

Explain the Management of Middle - Third Perforation Same to coronal one-third perforation, except defects located more deeper from the access cavity. For successfully

Explain about sex chromosomes, What is the other name given to sex chromos...

What is the other name given to sex chromosomes? Sex chromosomes are also known as allosomes (the other chromosomes that are not sex chromosomes are known as autosomes).

Sources of pollution, There are two main sources of pollution: (1). Nat...

There are two main sources of pollution: (1). Natural Sources:             (a) Volcanic ash             (b) Marsh gas (CH4) released from decay of organic matter.

Thymus gland, THYMU S GLAND Flat, bilobed gland located in the medi...

THYMU S GLAND Flat, bilobed gland located in the mediastinal space in front of heart. Well developed in new born child and grows upto puberty but starts degenerating the

What are the luria''s methods and theories, What are the Luria's methods an...

What are the Luria's methods and theories Adhering to our theory that the Luria Nebraska bears little resemblance to Luria's methods and theories, there seems little point in i

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd