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Tumor Suppressor Genes
Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-
NEO-LAMARCKISM Modem modified form of Lamarck theory is regarded as Neo-Lamarckism. Mc Dougall (1938) found that time taken for training the mice was reducing gradually
Autumn (fall) overturn In autumn or early winter the air temperature falls, resulting in the cooling of the surface waters. When the surface water cools to 4°C it becomes dens
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Triglyceride and cholesterol synthesized in the liver are secreted in very low density lipoprotein (VLDL) particles which serve to transport the lipids to the periphery. VLDL form
What do you Understand by Amphid? Unique to the nematodes, these paired sensory structures are located on the sides of the head. An external pore leads to an inner chamber and
Abnormalities in the lipid profile are found in patients with diabetes mellitus. The lipid abnormalities increase the risk of heart disease in diabetics and hence should be regular
Define Behaviour and Life Style Modifications for Weight Reduction Plan? Behaviour and life style modifications are an integral part of the weight reduction plan. They are base
How to increase in the amount of glucokinase in liver Consumption of a meal rich in carbohydrate or administration of insulin initiate an increase in the amount of glucokin
Describe about the term - Neuropsychological assessment Neuropsychological assessment has its roots in neurology, the branch of medicine that focuses on the nervous system and
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