Tumor suppressor genes, Biology

Assignment Help:

Tumor Suppressor Genes

Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-


Related Discussions:- Tumor suppressor genes

What type of selection is being demonstrated, If a cow develops a preferenc...

If a cow develops a preference for eating white four o'clock flowers and ignoring pink and red four o'clock flowers, what type of selection is being demonstrated? Would the cow eve

Developments in the area of nutrient-gene interactions, Define Developments...

Define Developments in the Area of Nutrient-Gene Interactions? This unit introduces you to the recent developments in the area of nutrient-gene interactions. We will first revi

Respiratory lining of human lung, Normal 0 false false fals...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Define the left cerebral cortex, Which of the following is true for a prima...

Which of the following is true for a primary motor cortex (M1) corticospinal interneuron that produces action potentials during movements of the big toe of the right foot? A. A

What is multiple alleles , What is Multiple Alleles ? Obviously, diploi...

What is Multiple Alleles ? Obviously, diploid organisms, such as humans can have only two different alleles for a certain gene locus. However, new alleles are continuously bein

What is the echocardiogram, What is the Echocardiogram ? When doubts pe...

What is the Echocardiogram ? When doubts persist whether a patient has CHD or not despite a thorough clinical exam and chest X-ray, ECG, and hyperoxia test, an echocardiogram s

Explain the chloride permeability, An impermeable membrane separates one li...

An impermeable membrane separates one liter of a 1M KCl solution in the left compartment from one liter of 1M NaCl solution in the right compartment.  At 2 AM today the membrane be

How are bacteria are classified, Q. How are bacteria are classified accordi...

Q. How are bacteria are classified according to their need for oxygen? According to their need of oxygen bacteria are classified into anaerobic those that survive without oxyge

Genitals examination of new born, Genitals check (in female), if ...

Genitals check (in female), if labia majora covers labia minora. In premature infant labia minora is not covered fully by labia majora.  check for discharge from vagin

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd