Tumor suppressor genes, Biology

Assignment Help:

Tumor Suppressor Genes

Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-


Related Discussions:- Tumor suppressor genes

How the respiratory system in aquatic molluscs characterized, Q. How is the...

Q. How is the respiratory system in aquatic molluscs characterized? What adaptive respiratory structure do terrestrial molluscs present? In terrestrial molluscs the rich vascul

What is physiology root pressure explain briiefly, What is Physiology: Root...

What is Physiology: Root Pressure explain briiefly? Transport of water, minerals and nutrients within vascular plants is dramatically different from animals such as humans. Whe

Indications for surgery-pulmonary regurgitation, Indications for Surgery : ...

Indications for Surgery : Patients usually present with fatigue, dyspnoea and ventricular arrhythmias. If they have additional tricuspid regurgitation, pulmonary valve replacement

History of psychiatric nursing, History of Psychiatric Nursing: In 187...

History of Psychiatric Nursing: In 1873, Linda Richards, developed better nursing care in psychiatric hospitals, and organized nursing services and educational programmes  in

How can the reactions of the nervous system be classified, Q. Concerning vo...

Q. Concerning volition of the individual how can the reactions of the nervous system be classified? The efferences (reactions) of the nervous system can be classified into volu

To test the effects of temperature on the activity of yeast, To test the ef...

To test the effects of temperature on the activity of yeast Make up a quantity of bread dough .Stir a yeast cake in water and methodically mix the yeast with the dough. Divide

Describe different animal groups, Describe different animal groups a) C...

Describe different animal groups a) Could  comprehensively  compare  and  contrast  the  behaviours  exhibited  by  social animals rather than describe different animal groups

What are the apical meristems, What are the apical meristems? Which kind of...

What are the apical meristems? Which kind of plant growth does this meristem promote? The Apical meristems are those primary meristems found in the apex of the stem as well as

What are vitamins, What are vitamins? What are the main vitamins needed by ...

What are vitamins? What are the main vitamins needed by humans? Most vitamins are coenzymes (fundamental substances for the enzyme functioning) that are not formed by the organ

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd