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Tumor Suppressor Genes
Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-
Explain the endochondral ossification The second type of osteogenesis is endochondral ossification. This process is different from intramembranous ossification in that it occur
Q. What are a few diseases characterized by progressive loss of the axonal myelin sheath? Multiple sclerosis is a severe disease caused by progressive destruction of the myelin
uses and advantages and disadvantages of immunolocalization
Define role of Lipids in Controlling Gene Expression? In the lipogenic pathway, the genes that encode the enzymes of the fatty acid synthase complex are co-ordinately expressed
Examples of sex-limited traits
How are grasslands classified? Grasslands might be classified into steppes and savannahs. In the steppes the prevailing vegetation is grass, as in the pampas of South America
why is it necessary to grind the food samples before testing?
Evolution of Metazoa The sponges, coming under phylum Porifera are the closest to Protista, and can perhaps be regarded even as a colony of protists rather than being multicel
What is Metallic implants Metallic implants undergo one or more several surface modifications to enable them to become suitable for implantation. These modifications are passiv
Q. What are the main human diseases caused by prions? The major known human diseases of such type are the Creutzfeldt-Jacob disease (CJD), the kuru and the Gerstmann-Sträussle-
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