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Tumor Suppressor Genes
Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-
TYPES E.R. consists of two types - 1. Rough E.R. 2. Smooth E.R. R o ugh E.R. S m o o th E.R.
Why are euglenas involved in polemics related to their taxonomic classification? Euglenas are included in taxonomic polemics because they tend to be classified sometimes as pro
REASON S FOR GROWTH OF POPULATION - The human population explosion is mainly a result of reduced death rate. Main reasons for it are - 1 . Protection from natura
Research to Improve Health Care Delivery: Today, much of health care delivery system remains imitative and intuitive rather than innovative, creative or scientific in
mitochondria?
Lactation tetany of mares (eclampsia, transit tetany) Hypocalcaemia in mares causes lactation tetany, which is characterized by abnormal behaviour, in coordination and tetany.
Is there interphase again between meiosis I and meiosis II? There is no interphase nor DNA duplication among the divisions of meiosis. Only a short interval called diakinesis h
Describe Aortic Regurgitation Murmur in Chronic AR Murmur ? Characteristic: High pitched, decrescendo murmur, immediately after S2 and extending through and part or all of dias
What is Cloning Cloning: Somatic (ie 2N) cell from original female cat removed (nucleus has mutated allele), fertilised egg extracted from another cat, nucleus removed, and egg
What is the taxonomy of protozoa?
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