Tumor suppressor genes, Biology

Assignment Help:

Tumor Suppressor Genes

Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-


Related Discussions:- Tumor suppressor genes

Rate of transport with increasing solute, Based on the information given in...

Based on the information given in each description, determine if the transporter is likely a channel or a carrier. This transporter shows increasing rate of transport with increasi

Fats are essential for meeting nutritional need of essential, Why Fats are ...

Why Fats are essential for meeting nutritional need of essential? Fats are essential for meeting nutritional needs of essential, fatty acids like linoleic acid (n-6) and alpha

Define major structures of chloroplasts, Q. What are the major structures o...

Q. What are the major structures of chloroplasts? Chloroplasts are involved by two membrane layers the inner and the outer membranes. Inside the organelle the formative unit is

Argon, will argon tend to form bonds with other elements?

will argon tend to form bonds with other elements?

Replication of chromatin, Whenever a chromosome is replicated the replicati...

Whenever a chromosome is replicated the replication machinery passes by the nucleosomes without deleting the histones from the DNA. How this happens is since not fully understood.

Islet of langerhans, Islet of Langerhans: They are insulin-producing tissue...

Islet of Langerhans: They are insulin-producing tissues. It was discovered by Paul Langerhans in 1869. These cells are in groups and look like islands in the pancreas. There are ab

What is the role of the nad molecule in glycolysis?, What is NAD? What is t...

What is NAD? What is the role of the NAD molecule in glycolysis? NAD (nicotinamide adenine dinucleotide) is a hydrogen acceptor essential as reductant (to receive hydrogen) in

Determine the human genome project, List three important discoveries that r...

List three important discoveries that resulted from the Human Genome Project. Answers should contain three of the following: Only about 2 percent of the human genome encodes p

Updating by deletion, Updating by Deletion DELETE FROM ENROLMENT WHERE...

Updating by Deletion DELETE FROM ENROLMENT WHERE StudentId = SID ('S4'); As you can see, this differs from Example by the addition of the noise word FROM. The expression SI

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd