Tumor suppressor genes, Biology

Assignment Help:

Tumor Suppressor Genes

Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-


Related Discussions:- Tumor suppressor genes

State fluid exchange between blood plasma in a capillary, Which of the foll...

Which of the following statements are true for fluid exchange between the blood plasma in a capillary in the leg and the interstitial spaces surrounding that capillary? A. Bloo

Rabbit, reproductive system of rabbit

reproductive system of rabbit

Nature of disease, Q. Nature of disease? Education is very important fo...

Q. Nature of disease? Education is very important for diabetics because it is a lifelong disorder. In order to enable the patient to lead a healthy and a good quality Life free

Cells, what are the buildings blocks of life?

what are the buildings blocks of life?

Biota of pelagic zone, Biota of Pelagic Zone Pelagic region constitute...

Biota of Pelagic Zone Pelagic region constitutes 90 per cent of the total ocean surface and is less rich in species and numbers of organisms than the two regions discussed bef

Can you illustrate compensation point, Q. What is compensation point? What ...

Q. What is compensation point? What is the inference of the compensation point for the plant growth? The photic compensation point is the photic energy intensity under which ae

Agro-industrial byproducts, Agro-industrial byproducts Agro-industrial...

Agro-industrial byproducts Agro-industrial by-products in Southeast Asia are available in plenty, due to the emphasis on crop cultivation. By-products of agro-industries repre

Glycolysis, Glycolysis Oxidation of glucose is called as glycolysis.Glu...

Glycolysis Oxidation of glucose is called as glycolysis.Glucose is oxidized to either lactate or pyruvate. Under aerobic conditions and the dominant product within most tissues

Explain imiquimod, Imiquimod (Aldara) This immunomodulator is FDA-appro...

Imiquimod (Aldara) This immunomodulator is FDA-approved for topical treatment of external and perianal genital warts, which are caused by papillomavirus. Gradual clearance of w

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd