Tumor suppressor genes, Biology

Assignment Help:

Tumor Suppressor Genes

Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-


Related Discussions:- Tumor suppressor genes

Can you explain vestibular system, Q. What is the vestibular system? How do...

Q. What is the vestibular system? How does it operate? The vestibular system is the part of the ear that participates in the regulation and control of the equilibrium of the bo

Iodine - mineral elements, IODINE The element is available is drinking ...

IODINE The element is available is drinking water, vegetables and fish. Table salts are also compulsorily iodized to provide iodine in the diet. All sea foods are rich in

What is the main risk factor for skin cancer, Q. What is the main risk fact...

Q. What is the main risk factor for skin cancer? The major risk factor for skin cancer is solar exposition of the skin without protection against ultraviolet radiation (a poten

State the term supply shortly, State the term supply shortly. Supply...

State the term supply shortly. Supply: Potential firms or businesses into the market which are willing and capable to supply various quantities of a good or service at a

Can you explain about krebs cycle, Q. Why can it be said that each glucose ...

Q. Why can it be said that each glucose molecule runs the Krebs cycle twice? Each glucose molecule "cycles" the Krebs cycle twice because after glycolysis each used glucose has

Explain the assessing and monitoring of peri-implant, Explain the assessing...

Explain the assessing and monitoring of peri-implant The parameters used for assessing and monitoring the peri-implant conditions need to be understood and applied judiciously

How is excretion done in fishes, How is excretion done in fishes? Fish...

How is excretion done in fishes? Fishes have a pair of kidneys that filtrate the blood. Bony fishes excrete nitrogen as ammonia, NH 3 , (they are ammoniotelic) and cartilagino

Current approach of liberal management in peptic ulcer, Q. Current approach...

Q. Current approach of liberal management in peptic ulcer? Current approach of liberal management in peptic ulcer medical nutrition therapy postulates: It is the individual pat

What is consanguineal marriage, What is consanguineal marriage? Why is the ...

What is consanguineal marriage? Why is the appearing of genetic disease more probable in the offspring of a consanguineal marriage? The Consanguineal marriage is the marriage b

Define the term - cholera, Define the term - Cholera Cholera is caused...

Define the term - Cholera Cholera is caused by the gram negative,  V. cholerae, which is acquired by ingesting food or water contaminated  by faecal material from patients or

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd