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Tumor Suppressor Genes
Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-
Why do we need a family of proteins for cell adhesion (what is the advantage of having a family of proteins?)
Q. After the neurula stage and from its ventral portion to the dorsal how can the morphology of the embryo be described? In a schematic longitudinal section of the embryo after
State about Heller's Nitric Acid Test Take 1 ml concentrated (fuming) nitric acid in a test tube and add 2 ml of urine by means of a pipette by the side of the test tube and la
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Primary producers - Biotic Components The major primary producers of aquatic ecosystems (freshwater and marine) are various species of algae. In terrestrial ecosystems the ma
Determinants of Health Status The linkage between economic development and health was discussed in the previous unit. The present unit deals with an identification of the factor
What is intracellular digestion? Intracellular digestion, or cellular digestion, is the breaking in the interior of the cell of big molecules coming from outside or even from i
Bronchial Asthma Bronchial Asthma is characterized by increased responsiveness of the trachea and bronchi to various stimuli that cause narrowing of the airways and difficu
Many endangered plant species are currently being propagated by commercial growers and botanical gardens and the sold (as both plants and seeds) to government agencies. Conservatio
The Red Data Book Species judged as threatened are listed by various agencies as well as by some private organisations. The most cited of these lists is the Red Data Book. It
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