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Tumor Suppressor Genes
Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-
What is the cause of the immunodeficiency presented by AIDS patients? The cause of the immunodeficiency shown by AIDS patients is the destruction of CD4 T helper lymphocytes by
Explain the following terms in detail - Homology, Homologous ? Structures that have a similar evolutionary origin however different functions. The wing of a bat and a whale's fl
what is the advantage of being dark skinned?
Diarrhoeas disease: Diarrhoeas disease rank among th most leading causes of children's death in developing countries. We shall discuss two main problems in this section i.e.
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What does acute disease mean? An sharp disease is which does not last for a longer duration n has no weakness in the body
Q. What do you mean by Bone Implant Interface? It consists of remodelled bony tissue. For making it strong implant should not be overloaded during its organization period i.e.
Q. Can you explain Bacillus Cereus Poisoning? Ans. Bacillus cereus poisoning is caused by the organism which is a large (3-5 pm long .and 1-4 pm wide), gram po%tive,
What are the Symptoms of Brown-Sequard syndrome Symptoms of Brown-Sequard syndrome usually appear after an affected individual experiences a trauma to the neck or back. First s
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