Tumor suppressor genes, Biology

Assignment Help:

Tumor Suppressor Genes

Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-


Related Discussions:- Tumor suppressor genes

Explain the techniques of operation in post myocardial, Explain the Techniq...

Explain the Techniques of Operation used in post myocardial infarction ventricular septal defect? Normal 0 false false false EN-IN X-NONE X-NONE

Access through the crown-endodontics principles and practice, Access throug...

Access through the crown Advantages : -Allow for better isolation with the rubber dam -Better esthetic anf functioning. -Good coronal seal between visits Limitations : -Proc

What are some examples of biological activities, Q. What are some examples ...

Q. What are some examples of biological activities in which osmosis plays an significant role? Hemolysis destruction of red blood cells by entrance of water, the hydric regulat

Zoology, main external morphological feature that differentiates platyhelmi...

main external morphological feature that differentiates platyhelminthes from nematodes

Assignment, Structure and development of leaf

Structure and development of leaf

Explain fluids, Explain Fluids Fluids: Fluid diets are given to patien...

Explain Fluids Fluids: Fluid diets are given to patients with more advanced dysphasia or fractured jaws. The diet may include fruit juices, thin strained porridge with milk, e

Differential reinforcement of low response rate, Differential reinforcement...

Differential reinforcement of low response rate (DRL) This is used to encourage low rates of responding. Example: "If you ask me for a potato chip no more than once every 10 mi

What are the valves of the venous system, What are the valves of the venous...

What are the valves of the venous system? What is their function? The valves of the venous system are structures within the veins that permit blood to flow only in the normal w

Diabetic with hypertension, Kidney Disease   The target BP in chronic k...

Kidney Disease   The target BP in chronic kidney disease is set at 130/80.  This will retard the progression of renal function. The drugs recommended are the ACEI/ARBs. These c

Define diet for treatment for protein energy malnutrition, Define Diet for ...

Define Diet for Treatment for Protein Energy Malnutrition? Treatment of cases of kwashiorkor or marasmus involves mainly providing appropriate nutrition support. The child shou

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd