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Tumor Suppressor Genes
Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-
Describe Class Ophiuroidea in general way? Brittle stars have a central disc with five long, thin, flexible arms that can be detached from the body at will in times of danger.
SIGNIFICANCE OF FERTILIZATION - 1. In fertilization process number of chromosome are diploid in zygote. 2. During fertilization male & female chromosomes are combi
Explain about the term- Therapeutic Therapeutic approaches that scientists are pursuing include transplanting cells to replace those which are damaged or using growth factors
Ventricular Arrhythmias : These include premature ventricular contractions (PVC), ventricular tachycardia (VT) and ventricular fibrillation (VT). At times they may be respon
DEVELOPMENTAL DISORDERS - 1 . AMNIONITIS- Inflammation of amnion due to infection. 2 . ABORTION- Escape of a embryo prior to the stage of viability (ab
what is the function of the bladder in the bladder worm
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Q. What is the life cycle of Trypanosoma cruzi? The Trypanosoma cruzi is a heteroxenous parasite that is it has an intermediate host, the triatomine bug, and a definitive host,
Explain about the Color vision of human eye The human eye can see about 150 different colours in the visible spectrum (400- 750 nm). Red, green and blue are said to be the prim
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