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Tumor Suppressor Genes
Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-
Glycogenolysis Unlike glycogenesis, glycogenolysis is the breakdown of glycogen. Glycogen is broken down in the liver and muscle catalysed by the enzyme glycogen phosph
Explain the Behavioural Observations of the child Behavioural observations of the child are the second critical source of information available to the neuropsychologist. Qualit
Q. Function of Dopamine in consciousness? An increase in dopamine activity produces an increase in wakefulness. Dopaminergic neurons in the ventral tegmental areas are constant
Gluconeogenesis Gluconeogenesis is the procedure through that glucose is synthesized from smaller easier molecules such as lactate and pyruvate. Although the catabolic linear p
M a r e k ' s disease (MD) It is a lymphopoliferative disease of domestic chicken caused by a herpes virus. Of the known 3 serotypes of MDV, Serotype I includes all the o
Pentoses are carbohydrates form of five carbons. Deoxyribose is the pentose that constitutes DNA nucleotides and ribose is the pentose that is part of RNA nucleotides
Conclusions drawn from the Monohybrid Crosses From the results of his monohybrid crosses, following conclusions were obtained :- 1 . Law of Unit or Paired Factors (Po
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i hyalonema labled diagram with his genral characters and classification
Genes and Alleles The inheritance of any character can be studied only when thcre are two contrasting conditions, such as yellow versus green seed colour (as observed by Mendel
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