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Tumor Suppressor Genes
Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-
which area of the basal nuclei is responsible for controlling appendicular muscle tone?
GOLGI COMPLEX ( GOLGI APPARATUS = GOLGI BODY) The Nobel laureate, Camilla Golgi (1898) discovered the presence of a special, small group of interconnecting membranous s
Why is it important for chromosomes to be condensed during mitosis and decondensed during interphase? During mitosis the major problem to be solved is the correct separation of
Q. What are the effects of somatostatin for the pancreatic hormonal secretion? Somatostatin inhibits both glucagon and insulin secretions.
what is the function of dna primer
Abnormalities in the lipid profile are found in patients with diabetes mellitus. The lipid abnormalities increase the risk of heart disease in diabetics and hence should be regular
Onchology : This is the study of cancer. Oncology word meaning is mass, bulk & tumor. This is a branch of medicine which deals with tumors (cancer). The one who practices oncology
Describe the important factors of Hand washing Hand washing is an important practice to follow before doing any procedure for the patient. The infection can be transferred
The Basque people, who lived in the Pyrenees Mountains between France and Spain, have one of the highest frequencies of the d allele in the Rh system so far reported. In one study
C ampylobacter infection C a mpylobacter jejuni is the commonest species found in poultry. These are delicate organisms that may not survive outside the host unless prot
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