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Tumor Suppressor Genes
Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-
phyla of animal like protists that have free living members
Q. Show types of hiatus hernia? Depending on the extent of herniation and placement of stomach, it could be of two types: 1, Para Oesophageal Hernia (oesophagus is in normal
HARD Y - WEINBERG LAW - Proposed by G.H. Hardy and W. Weinberg in 1908 independently. The law states "the frequency of genes or alleles in a population remains constant
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Explain Risk Assessment Risk Assessment : The scientific evaluation of known or potential adverse health effects resulting from human exposure to food borne hazards
(a) Bedroom : · Do not place room heaters near any inflammable materials. · Do not use heaters
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Hypotension, hyperkalemia, taste disturbance, angiedema, renal insufficiency. In the absence of any symptoms of hypotension, and normal renal function and K + levels, the dosage
Define Protection of poly unsaturated fatty acids (PUFA) from oxidative damage? The major biological role of vitamin E is to protect PUFAs and other components of cell membrane
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