Tumor suppressor genes, Biology

Assignment Help:

Tumor Suppressor Genes

Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-


Related Discussions:- Tumor suppressor genes

What is an etiological agent of disease, Q. What is an etiological agent of...

Q. What is an etiological agent of disease? The etiological agent of disease is the agent that causes the disease. It may perhaps a living being, substance or environmental fac

Can enhancers work in trans, Can enhancers work in trans? That is, can an e...

Can enhancers work in trans? That is, can an enhancer on one piece of DNA activate a promoter on another piece of DNA. Propose an experiment to test this. Be sure to discuss any ap

Determine the uses of the gums, The use of the gums in various foods may af...

The use of the gums in various foods may affect the following functional properties: 1. Water-binding capacity 2. Rheological properties 3.  Capacity to form film or gel

Can you illustrate trna anticodon, Q. If a tRNA anticodon is CAA what is it...

Q. If a tRNA anticodon is CAA what is its corresponding mRNA codon? For the genetic code which amino acid does this codon codify? According to the C-G, A-U rule, the correspond

What are cell kind that form the xylem, What are cell kind that form the xy...

What are cell kind that form the xylem? What are the major features of those cells? The major cells of the xylem are the tracheids and the vessel elements (these only in angios

What is allantois, What is Allantois One of the extraembryonic eggs foun...

What is Allantois One of the extraembryonic eggs found in the amniote animals. The allantois contains the metabolic wastes created by the developing embryo. May also be involved

Explain changes in body tissue compartments - underweight, Explain the Chan...

Explain the Changes in Body Tissue Compartments - Underweight? The severity of nutritional deprivation determines the extent of changes in the body tissue compartments. The fir

What is the health monitoring of infant, Explain the Health Monitoring of I...

Explain the Health Monitoring of Infant? Infections are a major cause of malnutrition in children. For many of the preventable early childhood diseases, vaccines are now avail

Atoms, the mass number is used to calculate the number of _________in one a...

the mass number is used to calculate the number of _________in one atom of an elemement. In order to calculate the number of neutrons you must subtract the _______from the ______.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd