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Tumor Suppressor Genes
Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-
A fire hose ejects a stream of water at an angle of 38.8 ° above the horizontal. The water leaves the nozzle with a speed of 26.6 m/s. Assuming that the water behaves like a projec
Why Fish and Sea Foods are important for human Body? They are rich sources of proteins (20-25%) of a high biological value. Dry fishes contain more (60%) proteins since most of
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Phosphorylation of glucose Glucose is converted to glucose-6-phosphate since phosphorylated intermediates do not readily penetrate cell membrane and this commits glucose t
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Alterations occurring in meat and poultry Meat, as you already know, is rich in proteins and contains most of the essential amino acids. It is also rich in minerals such as c
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