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Tumor Suppressor Genes
Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-
Patients with heart failure have a high incidence of both symptomatic and asymptomatic arrhythmias. About 10 per cent of patients have syncope or presyncope resulting from ventr
Define the Physiological Changes in Infants? Let us briefly understand some of these changes as they bear important relationship to the care and development of infants. Some o
In certain instances differences in the morphology of genitalia between species make it impossible for normal mating to occur, and sympatric species tend to remain isolated. When t
In the prokaryotes, RNA transcribed from protein-coding genes or messenger RNA, mRNA, need little or no changes prior to translation. In reality, several mRNA molecu
Q. How is the extracorporeal digestion associated to predation in arachnids? Arachnids can inoculate poison to kill or paralyze their preys using structures called chelicerae.
A. In order to determine the atomic number of an element we need to know the number of protons in an atom. As we know that atom is neutral we can also take the number of electro
Some ecosystems possess relatively large number of species as compared to others. This is particularly true of tropical forests which exhibit a very rich-biodiversity. For example,
Define sex
What are the disadvantages of protozoa
EGESTION To give out undigested food from alimentary canal. Faeces can remain in colon for 36 hrs. then moving into rectum by gastro-colic reflex. Faeces consists of 3
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