Tumor suppressor genes, Biology

Assignment Help:

Tumor Suppressor Genes

Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-


Related Discussions:- Tumor suppressor genes

Determine the biocompatibility of the material, Determine the Biocompatibil...

Determine the Biocompatibility of the material It is a vital factor as we have discussed in detail in the preceeding part of this unit. The nature of the material and its surf

Explain the term - social attention and environmental influe, Explain the t...

Explain the term - Social Attention and Environmental Influences The importance of social environment and early experiences in neurodevelopment is increasingly recognised. Due

What do you mean by bleeding index, Q. What do you mean by Bleeding Index? ...

Q. What do you mean by Bleeding Index? This factor is applicable at this stage to evaluate the health of one stage implants in which the transmucosal component allows the forma

Measuring ecosystem diversity, Measuring ecosystem diversity is not easy, a...

Measuring ecosystem diversity is not easy, and ther e is no definite index for its measurement. It is generally assessed by the measure of species diversity in an ecosystem, often

A protein is normally found inside of a lipid bilayer, A protein is normall...

A protein is normally found completely within the inside of a lipid bilayer. The protein likely has: a) Mostly hydrophobic side chains, pointed outwards, with the peptide backbo

Oligosaccharides, OLIGOSACCHARIDES They are small-sized polymers of ...

OLIGOSACCHARIDES They are small-sized polymers of monosaccharides having 2 - 6 simple sugars, occasionally upto 9 - 10. Oligosaccharides are soluble in water, sweet to t

DNA damaged by alkylating agents, Q. DNA damaged by alkylating agents? ...

Q. DNA damaged by alkylating agents? 1. Some simple alkylating agents 2. Illustrations of products of alkylating agents 3.Many of these products can be repaired by excision rep

Solutions, how many grams of table sugar would you need to dissolved in wat...

how many grams of table sugar would you need to dissolved in water to produce 0.75 liters of a 0:25 molar acqeous solution of table sugar?

What are ganglia, What are ganglia? Ganglia (singular ganglion), or neu...

What are ganglia? Ganglia (singular ganglion), or neural ganglia, are structures located outside the central nervous system (for instance, beside the spinal column or near visc

Define trace elements for school children and adolescents, Define Trace ele...

Define Trace elements for school children and adolescents? Iodine requirements peak in adolescence. Consumption of iodized salt should be ensured. Adequacy of zinc for growth i

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd