Tumor suppressor genes, Biology

Assignment Help:

Tumor Suppressor Genes

Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-


Related Discussions:- Tumor suppressor genes

What is physiologic adaptation, Physiologic Adaptation Modeling is a su...

Physiologic Adaptation Modeling is a surface specific activity (apposition or resorption) that produces a net change in the size and/or shape of the bone. It is an uncoupled pr

What is the explanation for the bleeding, Q. What is the explanation for th...

Q. What is the explanation for the bleeding that accompanies menses? The hemorrhage that accompanies menses occurs because the endometrium is a richly vascularized tissue and t

Write in 5-6 lines about food pyramid, Write in 5-6 lines about food pyrami...

Write in 5-6 lines about food pyramid. The diabetes food pyramid divides food into six groups. These groups vary with each other on the basis of si-e occupied in the pyramid.

Spermiogenesis - spermatogenesis, Spermiogenesis - Spermatogenesis At ...

Spermiogenesis - Spermatogenesis At the end of the meiosis the spermatids appear as simple spherical cells with a centrally located nucleus. Their differentiation into sperm r

Define the interaction of vitamin c with iron, Define the Interaction of Vi...

Define the Interaction of Vitamin C with iron? Ascorbic acid powerfully enhances absorption of non- haem iron and reverses the inhibiting effect of tea and calcium phosphate. I

Types of osmotic exchanges, Types of Osmotic Exchanges The osmotic exc...

Types of Osmotic Exchanges The osmotic exchanges that take place between an animal and its environment are of two different types: Obligatory exchanges and Regulated

Use of nitrates and nitrites in microorganisms, Q. Explain the Use of nitra...

Q. Explain the Use of nitrates and nitrites in microorganisms? The use of nitrates and nitrites has been widely used in the curing of meat. The reduction of nitrates by bacteri

Annelida, why is the phylum annelida in trouble?

why is the phylum annelida in trouble?

Discuss eukaryotic replication, Question 1 Discuss eukaryotic replication ...

Question 1 Discuss eukaryotic replication Question 2 Write an account on eukaryotic transcription factors Question 3 Write a detailed account on eukaryotic translation e

Determine the major demographic processes, Determine the major demographic ...

Determine the major demographic processes? There are five major demographic processes, which are continually at work within the population namely, fertility, mortality, marriag

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd