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Tumor Suppressor Genes
Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-
How the Wet beriberi Developed Rapidly? Oedema is the significant feature of wet beriberi. It may develop rapidly and involve not only the legs but also the face, trunk and ser
How can Heart be affect Heart may be affected in two ways. One of the complications of diabetes is autonomic dysfunction which may disturb rhythm of heart beat and may lead to
In patients who have not received prior antibiotics and who will ultimately have blood culture positive endocarditis, it is likely that 95 - 100 per cent of all cultures obtained w
What are the types of digestion and of digestive system of platyhelminthes? Flatworms have incomplete digestive systems and they show intracellular and extracellular complement
what is comretun
What is the utility of fungi for some industries? Fungi are industrially used in the production of fermented beverage, cheese, bread etc. Some fungi are very significant for th
What is katal katal : the amount of enzyme that transforms 1 mol of substrate into product in one second.
what is cytoplasm?
Influence of Associated Ions The second important factor influencing the plant uptake of a given cation is the effects of the ions held in association with it. For instance, as
Q. Cnidarians and Poriferans do not have excretory systems. Do platyhelminthes have an excretory system? Platyhelminthes have a primitive excretory system made of flame cells
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