Tumor suppressor genes, Biology

Assignment Help:

Tumor Suppressor Genes

Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-


Related Discussions:- Tumor suppressor genes

Considerations for congestive cardiac failure, Q. Considerations for conges...

Q. Considerations for congestive cardiac failure? - Subjects with congestive cardiac failure often tolerate small frequent meals better than larger infrequent meals as these a

Basic planes of cleavage, Basic Planes of Cleavage The basic planes a...

Basic Planes of Cleavage The basic planes along which the egg and its daughter blastomeres are divided during early cleavage are: A. Meridional Plane - the cleavag

Evolutionary implications of natural regulation, Evolutionary Implications ...

Evolutionary Implications of Natural Regulation Many changes in abundance can be attributed to changes in extrinsic factors such as weather, disease or predation. But some cha

Explain about the duration of exercise for diabetics patient, Explain about...

Explain about the duration of exercise for diabetics patient After selecting an exercise, it is very important to know the vigorous nature, duration and timings of the exercise

Does the entire human genome into nucleosomes, How many of each type of cor...

How many of each type of core histone would it take to wrap the entire human genome into nucleosomes? How has evolution solved the problem of producing such a large number of prote

Natural and artificial ecosystem, Natural and Artificial Ecosystem i) N...

Natural and Artificial Ecosystem i) Natural ecosystems are those which are mostly free from human disturbances, such as tropical forests, grasslands, oceans, lakes and deserts.

How vaginal infections cause, How Vaginal infections cause Sulfonamide ...

How Vaginal infections cause Sulfonamide creams, other ''broad-spectrum'' vaginal preparations, and currently available preparations of Lactobacillus  species or dairy products

Determine which seed is best for your lawn, Assume that your yard has many ...

Assume that your yard has many tall trees that result in about fifty percent of the yard being shaded and fifty percent of the yard being exposed to full sun. The shaded areas and

How many progeny flies have vestigial wings, In the fruit fly Drosophila, a...

In the fruit fly Drosophila, a rudimentary wing called "vestigial" and dark body color called "ebony" are inherited at independent loci and are recessive to their dominant wild-typ

Define chromatography - basic separation technique, Define Chromatography -...

Define Chromatography - Basic Separation Technique? Chromatography is the most effective technique for the separation, purification and identification of one or more biological

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd