Tumor suppressor genes, Biology

Assignment Help:

Tumor Suppressor Genes

Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-


Related Discussions:- Tumor suppressor genes

Style of stigma interaction, Style of Stigma Interaction The style has...

Style of Stigma Interaction The style has been distinguished into two types: In open styles a stylar canal is present which is lined with a well-developed glandul

Explain the nutritional and functional role of potassium, Minerals :- Potas...

Minerals :- Potassium Food Source      Fruits, vegetables, meats Nutritional Functional role Essential nutrient: Deficiency is rare. Salt substitute: KCl may be

Describe animal which limits activity to period of dim light, Which term is...

Which term is used to describe an animal which limits its activity to periods of dim light at dawn and dusk? a) Diurnal (pron: die-ER-nal) b) Vesperal (pron: VESS-per-al)

Give some chlorine-releasing compound, Q. Give some Chlorine-releasing comp...

Q. Give some Chlorine-releasing compound? Of all the chlorine - releasing compounds, hypochlorites have been the choice disinfectants used in food industry. The hypoc

How different are the heart chambers, Q. Concerning the thickness of their ...

Q. Concerning the thickness of their walls how different are the heart chambers? The ventricle walls are thicker than the atrium walls since ventricles are structures responsib

Regression of primitive streak, Regression of Primitive Streak As...

Regression of Primitive Streak As the inward migration of cells by the primitive streak ends progressively along its anterior to posterior regions the streak slowly regre

Tricuspid excision-types of surgery, Tricuspid Excision :  For tricus...

Tricuspid Excision :  For tricuspid valve endocarditis with vegetations in drug users, valve excision is done by removing three cusps and chordae and papillary muscles. Later

Ram ventilation, Ram Ventilation Some fish do not use pumping action f...

Ram Ventilation Some fish do not use pumping action for gill ventilation. It has been known for long that large tunas cannot be kept alive in captivity unless they are put in

Three phases into which the hiv infection is often divided, Q. What are the...

Q. What are the three phases into which the HIV infection is often divided? The HIV infection is frequently divided into three phases the acute phase, from the infection to 1 u

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd