Tumor suppressor genes, Biology

Assignment Help:

Tumor Suppressor Genes

Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-


Related Discussions:- Tumor suppressor genes

Skin, what is the warmest and coldest parts of the boy

what is the warmest and coldest parts of the boy

Coral reefs, Coral reefs form in clear warm tropical seas and are particula...

Coral reefs form in clear warm tropical seas and are particularly well developed in the South Pacific. They are formed by accumulation in calcarious skeletons of tiny colonial anim

Pulse wave doppler, Pulse wave  transducer has one Doppler  crystal. This c...

Pulse wave  transducer has one Doppler  crystal. This crystal emits a short burst of ultrasound at a certain frequency [PULSE REPETITION FREQUENCY (PRF)].  The ultrasqund is reflec

Types of lysosomes, TYPE S OF LYSOSOMES (1 )      Primary Lysosomes ...

TYPE S OF LYSOSOMES (1 )      Primary Lysosomes or storage granules or protolysosome - The primary lysosomes are smaller in size, they contain hydrolytic enzyme in the form

Define half saturation test and full saturation test, Define Half Saturatio...

Define Half Saturation Test and Full Saturation Test? This test is specific to polysaccharides. The test is used to detect dextrin from starch. The details related to the test

What is single s2, What is Single S 2 In cyanotic TOF, S, consists enti...

What is Single S 2 In cyanotic TOF, S, consists entirely of A, as P, is attenuated by a deformed pulmonary valve when there is valvar steuosis and aorta is placed anteriorly re

Hydrarch - kinds of succession, Hydrarch - Kinds of Succession When su...

Hydrarch - Kinds of Succession When succession takes place in a wet area, that is, succession progresses from hydric to mesic conditions. This can be further subdivided as:

Describe about congenital cardiac conditions encountered, Describe about Co...

Describe about Congenital Cardiac Conditions Encountered in Adults ? The entire population of adults with CHD is constituted by patients whose cardiac malformations have a natu

Explain barrier techniques - protective clothing, Q. Explain Barrier techni...

Q. Explain Barrier techniques - Protective clothing? Protective outerwear is worn to reduce exposure to debris in spatter. Clinic jackets should have long sleeves, a high neck,

Adrenal medulla, ADRENA L MEDULLA The adrenal medulla develops from th...

ADRENA L MEDULLA The adrenal medulla develops from the neuroectoderm of the embryo. Medulla consists of chromaffin cells or phaeochromocytes. These cells are connected wi

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd