Tumor suppressor genes, Biology

Assignment Help:

Tumor Suppressor Genes

Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-


Related Discussions:- Tumor suppressor genes

Translation in prokaryotes, Term Translation or protein synthesis, is quite...

Term Translation or protein synthesis, is quite similar in eukaryotes and prokaryotes. We will look at the details of the process in prokaryotes and consider the differences in euk

Explain the regulation of breathing and blood pressure, Which is the brain ...

Which is the brain region responsible for the regulation of breathing and blood pressure? The neural regulation of breathing, blood pressure and other physiological parameters

What is biodiversity, Q. What is biodiversity? The Biological diversity...

Q. What is biodiversity? The Biological diversity is the variety of species of living beings of an ecosystem. In the ecosystems which are more biodiverse, like tropical forests

Preparation - culture medium, Preparation - Culture Medium Now that ...

Preparation - Culture Medium Now that you are familiar with the constituents the preparation of medium is quite simple. Several plant tissue culture media are now available

Human eye, Who first discovered eye anatomy?

Who first discovered eye anatomy?

Define the dietary and lifestyle modifications - obesity, Define the Dietar...

Define the Dietary and Lifestyle Modifications - Obesity? The management of obesity basically comprises the following three- pronged approach. a) Dietary modifications b)

Define the respiratory chain process, Q. Where in mitochondria does the pro...

Q. Where in mitochondria does the process called respiratory chain occur? Which are the products of the Krebs cycle used in that final phase of the aerobic respiration? Respira

Explain process to maintain the quality of frying oil, Maintaining the qual...

Maintaining the quality of frying oil  As frying continues, the level of oil in the fryer depletes. There are two beneficial frying fat quality factors affected during the fryi

Respiration, what are the organs of respiration in lower forms of animals?

what are the organs of respiration in lower forms of animals?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd