Tumor suppressor genes, Biology

Assignment Help:

Tumor Suppressor Genes

Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevents cells from undergoing neoplastic transformation. While tumor suppressor genes are inactivated by mutations or are deleted, the absence of their protein products permits malignant growth to occur. The most extensively studied disease caused through suppressor genes is the childhood tumor retinoblastoma (cancer of the retina). The gene included is Rb and the genotype of normal individuals is Rb/Rb. A prerequisite of tumor creation is the development of homozygosity or heterozygosity of the rb allele. The possible genetypes for retinoblastoma are, hence, rb/rb; rb/- or -/-


Related Discussions:- Tumor suppressor genes

Explain food borne toxic infections, Q. Explain Food borne toxic infections...

Q. Explain Food borne toxic infections? Ans. The food borne toxic infections, you may recall reading earlier, are caused by the ingestion of a large numbers of ent

Explain genetically modified foods, Normal 0 false false fa...

Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4

What are biopolymers, What are biopolymers? Polymers are macromolecule...

What are biopolymers? Polymers are macromolecules made by the union of various smaller identical molecules, called monomers. Biopolymers are polymers present in the living bei

Of what substances is the nucleolus made, Q. Of what substances is the nucl...

Q. Of what substances is the nucleolus made? Is there a membrane around the nucleolus? Nucleolus is a region within the nucleus made of proteins and ribosomal RNA (rRNA). It is

What is endocrine system explain, What is Endocrine System explain ? Th...

What is Endocrine System explain ? The endocrine system consists of glands, organs that secrete hormones. Endocrine glands are tissues that produce secretions within the body,

Explain about types of insulin, Q. Explain about types of Insulin? Thre...

Q. Explain about types of Insulin? Three types of Insulin is available. The type varies in how quickly it starts working (lowering blood glucose), time of peak activity (when t

Describe lipoprotein, Q. Describe Lipoprotein? Ans. There is consi...

Q. Describe Lipoprotein? Ans. There is considerable current interest in this lipoprotein, which consists of LDL with an additional apoprotein-apoprotein (a) attached to it

Measurement of species diversity, The measurement of species diversity prov...

The measurement of species diversity provides an important preliminary assessment of overall biodiversity. There are many ways by which species diversity is measured i.e. species r

Currents in estuaries, Currents in Estuaries Currents in estuaries are...

Currents in Estuaries Currents in estuaries are caused primarily by tidal action and river flow. Currents are generally confined to channels but velocities up to several knots

Define casein - tests for presence of exoenzymatic activity, Define Casein ...

Define Casein - Tests for Presence of Exoenzymatic Activity? Casein is a major milk protein composed of various amino acids linked through peptide bonds. Extra-cellular enzyme

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd