Tuberculosis - patients on haart, Biology

Assignment Help:

Patients on HAART

Rifamycins induce hepatic CYP3A4 enzymes and can accelerate metabolism of protease inhibitors and some non-nucleoside reverse transcriptase inhibitors (NNRTIs), decreasing their serum concentrations, possibly to ineffective levels. The degree to which each drug activates CYP3A4 differs: rifampin is the most potent and rifabutin the least. In addition, rifabutin is a substrate for CYP3A4; protease inhibitors slow its metabolism, increasing serum concentrations and possibly toxicity.

 


Related Discussions:- Tuberculosis - patients on haart

What are spontaneous mutations, 1. DNA damaga can be spontaneous or can be ...

1. DNA damaga can be spontaneous or can be 'Induced by external agents a. What are 'spontaneous' mutations? Give examples of causes of spontaneous mutations and the kinds od DNA

Where does the water resorbed after glomerular filtration, Q. Where does mo...

Q. Where does most of the water resorbed after glomerular filtration go? What are the other substances resorbed by the nephron tubules? Only 0.5 to 1% of the glomerular filtrat

How can i become involved in supporting brain research, How can I become in...

How can I become involved in supporting brain research? A. Here are some ways which you can support brain research: Join in activities of Brain Awareness Week. Dona

What do you mean by periodical, Q. What do you mean by Periodical? A pe...

Q. What do you mean by Periodical? A periodical is a publication appearing at regular intervals. Each issue is called a number and collectively these numbers comprise a volume.

Types of aortic stenosis-aortic stenosis-valve disease, Types of Aortic Ste...

Types of Aortic Stenosis:  Obstruction to left ventricular outflow is commonly at the valvar level. Less commonly it is at the sub valvar or supra valvar level. Sub valvar ob

What is ammensalim, Q. What is ammensalim? The Ammensalism is the ecolo...

Q. What is ammensalim? The Ammensalism is the ecological interaction in which an individual harms another without obtaining benefit. The Ammensalism is an inharmonious (negativ

Chordata and its characteristics, Phylum Chordata- Chordata name given ...

Phylum Chordata- Chordata name given by Balfour. Herst put hemichordata into separate phylum. Lamarck gave the word tunicata & vertebrata. Pisces classified by Rom

What are the types of neurons, According to the function of the transmitted...

According to the function of the transmitted neural impulse which are the types of neurons? How different are the concepts of afference and efference of the neural impulse transmis

Ecological pyramids - ecosystem, Ecological Pyramids - Ecosystem The a...

Ecological Pyramids - Ecosystem The ancient Egyptians constructed elaborate tombs called pyramids. The base of the pyramid is broad and it supports the upper levels of the str

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd