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Patients on HAART
Rifamycins induce hepatic CYP3A4 enzymes and can accelerate metabolism of protease inhibitors and some non-nucleoside reverse transcriptase inhibitors (NNRTIs), decreasing their serum concentrations, possibly to ineffective levels. The degree to which each drug activates CYP3A4 differs: rifampin is the most potent and rifabutin the least. In addition, rifabutin is a substrate for CYP3A4; protease inhibitors slow its metabolism, increasing serum concentrations and possibly toxicity.
Many vitamins are enzyme cofactors that cannot be synthesized by the organism and must be attained from the diet.
What is Cerebellum Cerebellum is situated under the cerebrum. Cerebellum has right and left lobes which are joined and form a part of pons. The function of the cerebrum is
A mother has brought her 2-week-old infant to the emergency department due to the baby's persistent and increasing jaundice. Blood testing reveals that the infant's unconjugated bi
Elaborates the Pathophysiology of ventricular septal defect? The shunt in the VSD is left to right. The magnitude of the shunt is determined by the size of the VSD and the, lev
What is the natural habitat of E.coli? The E.coli was first recognized in the colon region of large intestine and so it was given the name "coli" (found in colon) they are coli
economic importance
Define Vitamin K-dependent carboxylation? Vitamin K acts as a cofactor in the synthesis of g-carboxyglutamic acid (Gla) from glutamic acid residues required for the normal coa
difference between anaerobic respiration and fermentation
What are the classes in Phylum coelenterata?
PANCREA S - It is derived from the endoderm of the embryo. Structure . The pancreas lies inferior to the stomach in a bend of the duodenum. It is both an exocrine an
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