Tuberculosis - patients on haart, Biology

Assignment Help:

Patients on HAART

Rifamycins induce hepatic CYP3A4 enzymes and can accelerate metabolism of protease inhibitors and some non-nucleoside reverse transcriptase inhibitors (NNRTIs), decreasing their serum concentrations, possibly to ineffective levels. The degree to which each drug activates CYP3A4 differs: rifampin is the most potent and rifabutin the least. In addition, rifabutin is a substrate for CYP3A4; protease inhibitors slow its metabolism, increasing serum concentrations and possibly toxicity.

 


Related Discussions:- Tuberculosis - patients on haart

Animal biodiversity, Discuss why Obelia is considered to be of special inte...

Discuss why Obelia is considered to be of special interest in Zoology as an animal showing an intermediate grade of organization.

#ALIMENTARY SYASTEM.., #in which part of alimentary canal oblique muscle fo...

#in which part of alimentary canal oblique muscle found?

Shows evidence to see the in environment abd ecology, Shows evidence of the...

Shows evidence of the ability to see the interaction between environment / ecology and genetics /  evolution Some candidates may recognise that evolution can result in less no

Intermediary metabolism, High Energy Compounds Primary need of the animal b...

High Energy Compounds Primary need of the animal body from the nutrients is energy. Free energy is the term used to denote the energy available to do useful work. Anabolic or synth

Neutralize acid rain because water is buffered, Select all that are true or...

Select all that are true or correct regarding a buffer: alternately donating and accepting ions a set of chemicals that work together to resist pH change often a weak acid or base

LIFE, What is life?

What is life?

Explain continuous full - thickness incision, Q. Explain Continuous full - ...

Q. Explain Continuous full - thickness incision? Continuous full - thickness incisions are indicated for a variety of situations outlined below. This type of incision may be us

Define the term- species, What is a species? A species is a set of livi...

What is a species? A species is a set of living beings able to cross between themselves generating fertile offspring. This concept though does not apply to individuals of ex

Explain vitamin k as an essential fat soluble micronutrient, Explain Vitami...

Explain Vitamin K as an essential fat soluble micronutrient? Vitamin K is an essential fat-soluble micronutrient the only unequivocal role in health is in the maintenance of no

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd