Tuberculosis - patients on haart, Biology

Assignment Help:

Patients on HAART

Rifamycins induce hepatic CYP3A4 enzymes and can accelerate metabolism of protease inhibitors and some non-nucleoside reverse transcriptase inhibitors (NNRTIs), decreasing their serum concentrations, possibly to ineffective levels. The degree to which each drug activates CYP3A4 differs: rifampin is the most potent and rifabutin the least. In addition, rifabutin is a substrate for CYP3A4; protease inhibitors slow its metabolism, increasing serum concentrations and possibly toxicity.

 


Related Discussions:- Tuberculosis - patients on haart

How structure of the subunits changed, The holoenzyme is denatured by heat ...

The holoenzyme is denatured by heat at very high temperature. It is found that two polypeptides, although denatured, contains chains that remain together as a unit, while two other

Explain cultivation of microorganisms, Explain Cultivation of microorganism...

Explain Cultivation of microorganisms It is for  the production of food colourants has attractions, these must be measured against the financial legislative and user constraint

Explain the associated procedure of reinforcement of patch, Explain the Ass...

Explain the Associated procedure of Reinforcement of Patch? Associated Procedures :  Coronary artery bypass grafting and repair of mitral valve are also carried out. P

Describe the classification of life in diversity of life, Describe the Clas...

Describe the Classification of Life in diversity of life? There are at least 10 million different kinds of living organisms inhabiting Earth. Many different organisms have comm

Explain academic dietitians, Teaching / academic dietitians Dietitians ...

Teaching / academic dietitians Dietitians process knowledge on all  aspects  01  nutrition  and dictetics.  They constantly keep  themselves updated  in  the necessary  informa

Explain rabies, Rabies  Rabies is highly prevalent in Africa, India, As...

Rabies  Rabies is highly prevalent in Africa, India, Asia and parts of Latin America, but the risk to travelers is low. Pre-exposure immunizationagainst rabies is recommended f

Isolate genomic dna, You may have heard in the news currently that a new sp...

You may have heard in the news currently that a new species of frog was discovered within a rainforest. You objective are to isolate genomic DNA and construct an expression libr

What is supraventricular arrhythmias, Q. What is Supraventricular Arrhythmi...

Q. What is Supraventricular Arrhythmias? Such arrhythmia tend to be reduced by the vagal withdrawal accompanying the onset of exercise.This and wandering pacemakers tend to rec

Combination of meat products, C o mbination of meat products Combinin...

C o mbination of meat products Combining meats and byproducts of different species to produce value added products results in complementation and supplementation of their qua

Class of mollusca - aplacophora, Class of Mollusca - Aplacophora Worm...

Class of Mollusca - Aplacophora Worm-like, no shell, head or excretory organs mantle with chitinous cuticle or scales or spicules mantle cavity posterior. Aplacophorans are a

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd