Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Explain exotic species, Explain exotic species? Describe with the help ...

Explain exotic species? Describe with the help of two examples how the exotic species disturb the native species of an ecosystem ?

Define effect of fat on quality and quantity of human milk, Define effect o...

Define effect of Fat on quality and quantity of human milk? Fat content of milk appears to be subject to variability as compared to other constituents. The average fat content

Define the disc electrophoresis, Define the Disc Electrophoresis? Disc ...

Define the Disc Electrophoresis? Disc electrophoresis has improved resolution and strong bands are obtained. It requires a two-gel system and several different buffers. The run

Define how the sticky ends are formed and get joined, a) A recombinant DNA ...

a) A recombinant DNA is formed when sticky ends of vector DNA and foreign DNA join. b) Define how the sticky ends are formed and get joined.

Skeletons of radiolarians, Skeletons of radiolarians The skeletons of ...

Skeletons of radiolarians The skeletons of radiolarians and foraminiferans form a primary constituent of ocean bottoms where they form 30% or more of the sediment. It is calle

State the term - rCBF, State the term - rCBF In rCBF, the participant i...

State the term - rCBF In rCBF, the participant inhales a small amount of a radioactive gas such as xenon, which is absorbed into the bloodstream and thus transported around the

Explain the scaling instrumentation of prothesis, Scaling Instrumentation o...

Scaling Instrumentation of prothesis Although stainless steel is generally the most effective material for removing calculus, it cannot be used with implants, because it scratc

What is the parasite that causes toxoplasmosis, Q. What is the parasite tha...

Q. What is the parasite that causes toxoplasmosis? How is the disease transmitted and what are its typical manifestations? The Toxoplasmosis is caused by the protozoan Toxoplas

Explain about iceberg phenomenon, Q. Explain about Iceberg Phenomenon? ...

Q. Explain about Iceberg Phenomenon? Phenomenon means a fact or occurrence that appears. Let us see how iceberg phenomenon is applied to Diabetes Mellitus (DM). Cases of dia

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd