Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Define the first step to envision the pattern of deformation, Define the fi...

Define the first step to envision the pattern of deformation. The first step in the analysis is to envision the pattern of deformation that would accompany such a failure. In t

Which is better to grow plants in rock sand or soil, Explain which is bette...

Explain which is better to grow plants in Rock sand or soil? Ans) When we grew plants inside, with no wind, and the plants in the rocks grew superior to the plants that were gr

What are the chronic complications of diabetes, Q. What are the Chronic com...

Q. What are the Chronic complications of diabetes? • Atherosclerosis: Degeneration of walls of the arteries due to fatty plaques - deposition on arterial walls. Diabetics ar

Artificial skin, Artificial Skin: The skin generated in vitro is in fac...

Artificial Skin: The skin generated in vitro is in fact the epidermis portion of skin only; when the epidermis is applied to the burnt part, this leads to the regeneration of d

Define role of zinc in controlling gene expression, Define role of Zinc in ...

Define role of Zinc in controlling Gene Expression? Zinc atoms have specific structural roles in enzyme molecules, as well as, in many other proteins and in bio membranes. Thes

How many types of gametes can be formed, How many different types of gamete...

How many different types of gametes can be formed by individuals of the following genotypes? What are they in each case a) AaBb b) AaBB c) AaBbCc d) AaBBCc e) AaBbcc f) AaBbCcDdEe

Define tests of cardiovascular endurance, Define Tests of Cardiovascular E...

Define Tests of Cardiovascular Endurance? Cardiovascular endurance or aerobic fitness is the ability to exercise continuously for extended periods without tiring. It can be me

Marine biomes, The marine biomes consist of the earth's oceans and its asso...

The marine biomes consist of the earth's oceans and its associated areas like the shorelines, islands, reefs and estuaries. The marine waters contain about 3.5 percent salt, mostly

Exercise and medications in bronchial asthma, Exercise Stress or em...

Exercise Stress or emotional upset  Medications Aspirin, non-steroidal anti-inflammatory drugs(NSAIDs), beta- blockers(including eye drops), cholinergic dr

What proportion of the progeny, In holly, serrated leaves are dominant to s...

In holly, serrated leaves are dominant to smooth-edged leaves, and red berries are dominant to green berries. Two holly plants heterozygous for leaf edge shape and berry color are

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd