Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

How is the excretory system of molluscs characterized, Q. How is the excret...

Q. How is the excretory system of molluscs characterized? Molluscs have one or two pair of spongelike nephridia, similar to kidneys

Define the role of addition of acetyl groups to histones, Creb binding prot...

Creb binding protein (CBP) is a histone acetyl transferase (HAT) protein. What role does the  addition of acetyl groups to histones play during development? A. The addition of

Bty100, 1. (a) Which physicochemical properties need to be regulated by the...

1. (a) Which physicochemical properties need to be regulated by the cell? Define chemical equilibrium and discuss how it is maintained by the cell. (b) Differentiate between facili

Soil temperature, Soil Temperature Soil temperature is known to influe...

Soil Temperature Soil temperature is known to influence water absorption and ultimately transpiration to a considerable extent. In many plants water absorption is reduced shar

Define isolated soybean proteins in infant formulas, Define isolated soybea...

Define isolated soybean proteins in Infant formulas? Infant formulas, where milk solids have been replaced by soy products, are well established commercial products. ISP is the

Probation/parole client , Write a report on a special probation/parole clie...

Write a report on a special probation/parole client and programs that have been situated to address this problem client. Focus on 1type of special requires offender (substance abus

Sexual selection, In this section you will be introduced to a variant of Da...

In this section you will be introduced to a variant of Darwinian concept of natural selection which he termed sexual selection. You may have observed very distinct and striking dif

Feeding habit, what is the mode nutrition exibited by tape worm?

what is the mode nutrition exibited by tape worm?

Give choice of catheters for ventriculography, Q. Give Choice of Catheters ...

Q. Give Choice of Catheters for Ventriculography? 1) Pigtail Catheter: This catheter developed by Judkins has end hole and side holes. The end hole permits insertion of the c

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd