Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Explain major divisions of the hypophysis, Q. What are the major divisions ...

Q. What are the major divisions of the hypophysis? What are their functions? The hypophysis is divided into two portions- the anterior hypophysis or adenohypophysis and the pos

Chest and leg wound complications, Chest and Leg Wound Complications ...

Chest and Leg Wound Complications :  The patients under going CABG are usually elderly, obese and nearly a quater of them are diabetic. So sonic of them get superficial or d

Angiosperms, Angiosperms  are the flowering plants. They first appeared at ...

Angiosperms  are the flowering plants. They first appeared at least 110 million years ago from the unknown gymnosperm ancestor, these flowering plants have risen to dominance in th

State the method of recombination or crossing-over, Which of the following ...

Which of the following statement is false regarding the method of recombination or crossing-over? A. Crossing-over takes place during prophase I of meiosis B. Recombination

What is anabolism, Q. What is Anabolism? Anabolism Anabolism is a pr...

Q. What is Anabolism? Anabolism Anabolism is a process of synthesis or making of larger or complex molecules from smaller molecules. These molecules are of different kinds l

Nutrition, definition of dietary factors. or what are dietary factors?

definition of dietary factors. or what are dietary factors?

Define water balance - hormonal control of fluid balance, Define Regulation...

Define Regulation of Water Balance - Hormonal Control of Fluid Balance? Hormonal control of fluid balance: When water intake is insufficient or water loss is excessive, the kid

Cancer lung, Cancer Lung Incidence of cancer lung is more in persons ...

Cancer Lung Incidence of cancer lung is more in persons who smoke. Environmental and industrial pollution is also a risk factor in the increase in incidence. Clinic

Explain the the methods of community and population, What is a community? ...

What is a community? What is the difference among the methods of community and population? A community is a set of populations of living beings that live in the similar region

Bacterial diseases-pigs, Pigs This is a sub-acute or chronic infection ...

Pigs This is a sub-acute or chronic infection manifested by abortion, sterility, high piglet mortality and orchitis in pigs. Br. suis causes brucellosis among pigs. It is morph

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd