Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

What is deoxynivalenol, Q. What is Deoxynivalenol? Deoxynivalenol (DON)...

Q. What is Deoxynivalenol? Deoxynivalenol (DON) is a far more common, but much less toxic, trichothecene and is produced by species such as F. graminearum and F. culmorum. LD

Explain the family nutrition approach, The Family Nutrition Approach Th...

The Family Nutrition Approach This involves relatives/family who  live in the client's household; in assisting  the client to make necessary dietary changes  to  prevent or  to

What do you mean by proteinuria, Q. What is proteinuria? Why is proteinuria...

Q. What is proteinuria? Why is proteinuria a sign of glomerular renal injury? Proteinuria means losing of proteins through urine under normal conditions proteins are too big to

Illustrate photochemical phase, Q. Which are the subproducts of the photoch...

Q. Which are the subproducts of the photochemical phase that are essential for the chemical stage of photosynthesis? The chemical stage of photosynthesis depends on ATP and NAD

What property of water helps, South Dakota and Oregon are at similar latitu...

South Dakota and Oregon are at similar latitudes, and yet, on average, Oregon has warmer winters and cooler summers than South Dakota does. What property of water helps account for

Define placental transfer of nutrients, Define Placental Transfer of Nutrie...

Define Placental Transfer of Nutrients? The placenta is n transitory structure developing during pregnancy and lies implanted on the uterine wall. It is connected with the foet

How is the respiratory system in aquatic molluscs, How is the respiratory s...

How is the respiratory system in aquatic molluscs divided? What adaptive respiratory structure do terrestrial molluscs present? Aquatic molluscs oxygenate their blood through g

What is the association between inflammation and fever, What is the associa...

What is the association between inflammation and fever? In the tissue region where inflammation happens bacterial toxins, cytokines, prostaglandins, interleukins and endothelin

Biology Project, what does the future look like with trash in the ocean?

what does the future look like with trash in the ocean?

What is atrial septal defect, What is Atrial Septal Defect ? Fig...

What is Atrial Septal Defect ? Figure: Anatomical location of Am Indication for Surgery :  The presence of an ASD or PAPVC (Partial Anomalous Pulmonary Venous Conn

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd