Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Explain the serial dilution process - plate counts, Explain the Serial Dilu...

Explain the Serial Dilution Process - Plate Counts? Dilution factor is the reciprocal of the dilution used. As number of microorganisms in original sample is not known, the ori

Problems of osmoregulation, Problems of Osmoregulation The water, some...

Problems of Osmoregulation The water, some inorganic salts, nutrient molecules are some of the important components of the body fluids. It is essential for the animals to main

Distal convoluted tubule, Normal 0 false false false EN...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Life as an expression of energy changes, LIF E AS AN EXPRESSION OF ENERGY ...

LIF E AS AN EXPRESSION OF ENERGY CHANGES - Energy is explained as capacity of body to do work. Energy may be as potential (stored) or kinetic (expended) energy. It ex

What is the senses explain their vision , What is the Senses explain their ...

What is the Senses explain their Vision ? Vision :  The human eye consists of structures which evolved together to focus light on a sensitive area called the retina. Light f

What is the major cell organelle involved in cell digestion, Q. What is the...

Q. What is the major cell organelle involved in cell digestion and what are the properties of that organelle that enable it to do the task? The organelles accountable for intra

Zoonoses disease-anthrax, Anthrax Anthrax is primarily a disease of th...

Anthrax Anthrax is primarily a disease of the herbivores and occurs in almost all parts of the world. The disease has declined recently throughout the world as a result of the

Homologous series, Homologous series A homologous series can be illust...

Homologous series A homologous series can be illustrated as a group of compounds in which the several members have similar structural features and identical chemical propertie

Stages of aerobic respiration, Stages of Aerobic Respiration: Glycoly...

Stages of Aerobic Respiration: Glycolysis (cytoplasm) Process 2ATP used for Glucose -> Fructose 1,6 bisphosphate Fructose splits into G3P and DHAP. DHAP

Inverse pcr, Inverse PCR is the variation of PCR which makes the amplifica...

Inverse PCR is the variation of PCR which makes the amplification of DNA segments of unknown sequence that flank DNA segments of the known sequence possible; in short, total DNA i

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd