Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

What is the trace element, What is a trace element and how are they importa...

What is a trace element and how are they important in organisms, give an example.

Cells, Where do the light reactions occur in prokaryotic and eukaryotic cel...

Where do the light reactions occur in prokaryotic and eukaryotic cells?

What are the main types of cancer that affect humans, Q. What are the main ...

Q. What are the main types of cancer that affect humans? An Excluding skin cancer, that are the more easily detected and so cases are registered in larger number, the main type

What are the hormones produced by the testicles, What are the hormones prod...

What are the hormones produced by the testicles and the ovaries? The testicles make androgenic hormones, the major of them being testosterone. The ovaries make estrogen and pro

What kinds of mutation in disease-causing bacteria, What kinds of mutation ...

What kinds of mutation in disease-causing bacteria might make them more dangerous Pathogenic bacteria will become more dangerous to us if mutations make them more virulent or r

Classification, claasification of phylum porifera

claasification of phylum porifera

What is the plasma membrane of the cell, Q. What is the plasma membrane of ...

Q. What is the plasma membrane of the cell? What are its major functions? The plasma membrane is the external membrane of the cell, it delimits the cell itself and a cell inter

State the concepts of soil- pedology and edaphology, State the concespts of...

State the concespts of soil- pedology and edaphology In the last two centuries of scientific study, two concepts or approaches to the study of soil have evolved.  One called  p

How sequences of events occur to activate protein kinase a, When glucagon b...

When glucagon binds to it's receptor on a liver cell, which one of the following sequences of events occurs to activate protein kinase A? -activation of G protein, activation of

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd