Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Introduction of quality attributes of food, Q. Introduction of Quality Attr...

Q. Introduction of Quality Attributes of Food? Seasonal fruits and vegetables are grown in plenty, and are available in their respective seasons in abundance. While choosing th

What are neurons, Question 1 Give the definition and describe the mechanis...

Question 1 Give the definition and describe the mechanism of Active transport. Passive transport with suitable examples Question 2 What are neurons? List out the

Explain Genetic equilibrium for genes with two alleles, What is the mathema...

What is the mathematical expression of the genetic equilibrium for genes with two alleles? Is this statistical distribution the same as the statistical distribution of the respecti

Hindbrain - cerebellum, HIND BRAIN - 1 .       CEREBELLUM - Li...

HIND BRAIN - 1 .       CEREBELLUM - Little part, lies below the posterior part of cerebrum & above the medulla oblongeta. It conists of median lobe vermis & 2 lat

Haversian canals and the volkmann canals of the bones, Q. What are the Have...

Q. What are the Haversian canals and the Volkmann's canals of the bones? Is the osseous tissue vascularized? The Haversian canals are longitudinal canals present in the osseous

Acute diarrhoea, Q. Acute diarrhoea? It must be evident from the table ...

Q. Acute diarrhoea? It must be evident from the table above that acute diarrhoea generally occurs in association with infections, poisons and drugs. Chronic diarrhoea on the ot

Describe food applications of alginate, Food Applications of alginate O...

Food Applications of alginate One of the most unusual properties of the alginates has been the ability of soluble alginate salts to produce attractive, edible gels or jellies.

What is the constitution of the cartilaginous matrix, What is the constitut...

What is the constitution of the cartilaginous matrix? The cartilaginous matrix is made of collagen fibers, mostly collagen type II, and of proteoglycans, proteins associated to

Onset of puberty in female, ONSE T OF PUBERTY IN FEMALE - Attains at t...

ONSE T OF PUBERTY IN FEMALE - Attains at the age of 13 by estrogen hormone. It includes - 1. Growt h of breasts 2. Growth

Why is pattern baldness more common in men than in women, Why is pattern ba...

Why is pattern baldness more common in men than in women? Pattern baldness is handled by the allele B. Testosterone interacts with the heterozygous genotype (BB′) to make baldn

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd