Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

What will be the final volume, Suppose a sample of 200 microliters of blood...

Suppose a sample of 200 microliters of blood needs to be diluted 1/50. How much diluents should be added and what will be the final volume? Show all steps.

How sugar is used in bakery application, How Sugar is used in Bakery Applic...

How Sugar is used in Bakery Application? In bakery applications, sugars are used to impart flavor, aroma and color. During the mixing process, excess gluten development can mak

State the lantern test of eye, State the Lantern Test  The patient nam...

State the Lantern Test  The patient names colours displayed in the lantern and the mistakes are analyzed. This is not the best method of testing because it depends on the natu

State about endocrine system, Endocrine System In endocrine system duct...

Endocrine System In endocrine system ductless gland or specialized cells release chemicals called hormones into the circulating blood. These hormones influence the functions of

Characteristics of a good fuel, (1)   It should have high "calorific value"...

(1)   It should have high "calorific value" or heat content. (2)   It should have "moderate ignition temperature". (lgnition temperature is the minimum temperature at which it s

Rhinosporidiosis (fungal-like agent), Rhinosporidiosis (Fungal-like agent) ...

Rhinosporidiosis (Fungal-like agent) Rhinosporidiosis is a chronic, non-fatal, granulomatous mycotic infection of nasal mucosa caused by Rhinosporidium seberi. R. seberi is curren

Valves of the heart, Valves of the Heart There are four valves which ...

Valves of the Heart There are four valves which are flap-like structures that function to maintain unidirectional (forward) blood flow through the heart chambers. These va

Homologous series, Homologous series A homologous series can be illust...

Homologous series A homologous series can be illustrated as a group of compounds in which the several members have similar structural features and identical chemical propertie

Explain the physiologic mechanism of osseointegration, Q. Explain the Physi...

Q. Explain the Physiologic mechanism of osseointegration It has been suggested that the physiologic mechanism for maintaining osseous integration is a sustained evolution in re

Explain prophylaxis with antimicrobial, Explain Prophylaxis with antimicrob...

Explain Prophylaxis with antimicrobial Prophylaxis with antimicrobials has decreased the incidence of surgical site infection after head and neck operations that involve an inc

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd