Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Complications of diabetes, Q. Complications of Diabetes? Diabetes, as y...

Q. Complications of Diabetes? Diabetes, as you know, is a lifelong disease. We have said earlier also that it can be controlled but not cured. Control of diabetes by ensuring n

Define meal pattern and feeding considerations, Define Meal Pattern and Fee...

Define Meal Pattern and Feeding Considerations? The meal pattern and the feeding considerations include the following: - Meal timings play an important role in ensuring adeq

What do you mean by polyphagia, Q. What do you mean by Polyphagia? Incr...

Q. What do you mean by Polyphagia? Increased Hunger (Polyphagia): As patient is losing more sugar in the urine, he feels hungry very soon and tends to take more food. It is cal

Explain briefly pinocytosis , Unlike the phagocytosis, that is a regul...

Unlike the phagocytosis, that is a regulated form of endocytosis carried out by a small number of cell category, pinocytosis is a constitutive process which happens continuously in

Explain thetechnique of total anomalous surgery, Explain theTechnique of to...

Explain theTechnique of total anomalous Surgery ? Corrective surgery is undertaken as an emergency procedure after diagnosis has been confirmed by two-dimensional echocardiogra

Where can rna be found within cells, Where can RNA be found within cells? ...

Where can RNA be found within cells? In the eukaryote cell nucleus RNA can be found dispersed in the nuclear fluid, with DNA, and as the main constituent of the nucleolus. In c

What are the differences between minerals and ores , Menerals are naturally...

Menerals are naturally occurring inorganic solids with a crystalline structure and a definite range of chemical formula. Ores are concentrations of minerals in rock.

Human activity lead to the extinction of a species, In what ways could huma...

In what ways could human activity lead to the extinction of a species in an area? Human activity could lead to extinction of a species by (a) over-hunting, e.g. elephants, rhin

Give examples of both aerobic and anaerobic exercises, Give examples of bot...

Give examples of both aerobic and anaerobic exercises Games like foot ball and basket ball, involve  both aerobic and anaerobic exercises. As you are aware, in modern times a n

What food items include in clear liquid diet, What Food items include in cl...

What Food items include in clear liquid diet -  Clear, fat free soups/broths -  Light coffee, tea (without milk or cream) -  Strained fruit juices -  Tender coconut wa

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd