Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Show overall management of diabetes, Q. Show overall management of diabetes...

Q. Show overall management of diabetes? Diabetes as we all know is a disease with ever increasing prevalence in' our country. It can be described as a disease characterized by

Floral apex, Floral Apex Each plant must pass through a minimal 'ripe...

Floral Apex Each plant must pass through a minimal 'ripeness to flower' stage. That is, even to perceive and respond to a specific photoperiodic regime, a plant must be ready

Parts of a typical flower with all its definations , parts of a typical fl...

parts of a typical flower? define its parts and internal parts completely? show complete colourful diagram?

Illustrate oil-bearing materials, Illustrate oil-bearing materials Oil...

Illustrate oil-bearing materials Oil contents for vegetable oil-bearing materials vary between 18% and 68% of the total weight of the seed, nut, kernel or fruit as indicated i

Heterotrophs, Collect images of heterotrophs and make a Powerpoint Presenta...

Collect images of heterotrophs and make a Powerpoint Presentation on them

What is the general function of leukocytes, Q. What is the general function...

Q. What is the general function of leukocytes? What are leukopenia and leukocytosis? The general function of leukocytes is to participate in the made inside the body or defense

How are fishes characterized, Q. Fish identity card. How are fishes charact...

Q. Fish identity card. How are fishes characterized according to examples of representing beings, skin, basic morphology, circulation, nitrogen waste, respiration, thermal control

Transcription of a eukaryotic protein-coding gene, 1. Describe how the vari...

1. Describe how the various molecular mechanisms act to regulate transcription of the genes within the lactose operon of E. coli . 2. Transcription of a eukaryotic protein-codi

What emergency department after an automobile accident, An 22 year old man ...

An 22 year old man is admitted to the emergency department after an automobile accident. He has not lost a large amount of blood, but he suffers from a severe crush injury to hi

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd