Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Nephridia of worms, Normal 0 false false false EN-IN ...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Explain the pour plate method, Explain the Pour Plate Method Isolated c...

Explain the Pour Plate Method Isolated colonies can also be obtained by pour plate method. The method involves mixing of small volume of microbial suspension with molten nutrie

What is working of mouth in human body, What is Working of Mouth in human b...

What is Working of Mouth in human body? Food enters the digestive system through the mouth, where it is processed by the teeth and mixed with saliva, prior to being swallowed.

Isomerisms types of unsaturated fatty acids, Unsaturated fatty acids show ...

Unsaturated fatty acids show different types of  isomerisms. We have already learnt about the.concept of  isomerism  in  the  last unit. You would  realize that fatty acids with s

What is peri-implant disease, Q. What is Peri-Implant Disease? The term...

Q. What is Peri-Implant Disease? The term peri-implantitis is used to describe the boneloss around an implant. This may be induced by stress or bacteria or a combination of bot

What are bacteriophages, What are bacteriophages? Bacteriophages are vi...

What are bacteriophages? Bacteriophages are viruses specialized in parasitism of bacteria. They are used in genetic engineering as molecular cloning vehicles to insert recombin

Ink prints of leaves, Ink prints of leaves Place a small quantity of pr...

Ink prints of leaves Place a small quantity of printer's ink on a sheet of glass or a tile. Roll the ink into a thin yet layer with a rubber roller. Place a leaf, vein side up,

Conclusions from the monohybrid crosses, Conclusions drawn from the Monohyb...

Conclusions drawn from the Monohybrid Crosses From the results of his monohybrid crosses, following conclusions were obtained :- 1 .       Law of Unit or Paired Factors (Po

Define control of infections for treatment for pem, Define Control of infec...

Define Control of infections for treatment for pem? Appropriate antibiotics should be started immediately since infections are the immediate cause of death in many children. Ch

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd