Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Describe the use of sorbates acid in microorganisms, Q. Describe the use of...

Q. Describe the use of Sorbates acid in Microorganisms? Sorbic acid is an unsaturated carboxylic acid whose salts as sodium, calcium or potassium are used in foods upto

Use values of biodiversity, Despite its importance, determining the value o...

Despite its importance, determining the value or worth of biodiversity is complex and often a cause for debate. This is largely due to the fact that the worth placed on biodiversit

Determine the tenant of the cell theory, Determine the tenant of the Cell T...

Determine the tenant of the Cell Theory Which of the following is not a tenant of the Cell Theory as postulated by Mathias Schleiden and Theodor Schwann? A. All organisms a

Respiration, How does Respiration in animals

How does Respiration in animals

Nutrition, prove oxygen is produced during photosynthesis in the presence o...

prove oxygen is produced during photosynthesis in the presence of light

Define assessment of calcium status and calcium requirements, Define Assess...

Define Assessment of Calcium Status and Calcium Requirements? There is no biochemical indicator, which can clearly reflect calcium status. It has also been seen that in case of

Describe what happens during activation of the lac operon, Describe what ha...

Describe what happens during activation of the lac operon. Lactose binds to the repressor protein, which causes the repressor protein to be released from the operator site. Th

State the types of bone density, State the types of bone density Misch ...

State the types of bone density Misch classified bone density into following types (1988) D1. Dense cortical bone- which is almost never observed in maxilla and approximatel

Hypothetical bacterial cell, A microbiology student isolated a hypothetical...

A microbiology student isolated a hypothetical bacterial cell that seems to quadruple every generation. Knowing that binary fission is an exponential function, derive a mathematica

Cell membrane, CELL MEMBRANE As discrete units of life  all living cell...

CELL MEMBRANE As discrete units of life  all living cells are separated from each other and from their external environment by an  extremely delicate (75 A to 100 a= 0.00075 to

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd