Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Management goals for diverticular disease, Q. Management goals for divertic...

Q. Management goals for diverticular disease? The management goals discussed above are basic to prevention of diverticulitis. However, diet therapy during diverticulitis may b

What is the significance of pharyngeal gill slit, What is the significance ...

What is the significance of Pharyngeal gill slit ? Lateral opening in the wall of the pharynx which allows water to enter into the mouth and exit through the pharynx. This is on

Epidemiological association between hemophilia and hiv, Q. What is the epid...

Q. What is the epidemiological association between hemophilia and HIV infection? In the past the blood banks did not usually perform HIV detection tests and many hemophilic pat

Virus is in an inactive state, Q. What is signifying when it is said that a...

Q. What is signifying when it is said that a virus is in an inactive state? Viruses considered in inactive state are those whose genetic material is within host cells without a

Why it have been so difficult for radially symmetrical, Unlike bilaterally ...

Unlike bilaterally symmetrical animals, radially symmetrical animals are almost never able to move themselves from place to place. Why might it have been so difficult for radially

State the term - early therapeutic intervention, State the term - Early the...

State the term - Early therapeutic Intervention Since outcome may be ameliorated by well timed and appropriate treatment, the prevailing belief is that dysfunction should be id

Explain the safe requirement of nutritional needs, Explain the Safe Require...

Explain the Safe Requirement of nutritional needs? Given the individual variations in nutritional requirements that have been discussed earlier, the lowest continuing intake le

Lab report, Why making a smoke print of a leaf

Why making a smoke print of a leaf

Explain restrictive cardiomyopathy, Q. Explain Restrictive cardiomyopathy? ...

Q. Explain Restrictive cardiomyopathy? It is a systemic or idiopathic disorder of the myocardium with clinical and hemodynamic features of diastolic dysfunction, closely simula

Self- vs. cross-pollination, Self- vs. Cross-Pollination A major adva...

Self- vs. Cross-Pollination A major advantage of self-pollination is its certainty. Continued self-pollination over many generations, however, results in weaker progeny. This

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd