Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Explain global burden in the history of mart disease, Explain Global burden...

Explain Global burden in the history of mart disease? In 2001, 17 million people died of CVD of all types. The most important causes were ischemic heart disease (IHD), Hyperten

Describe splitting of in second heart, Describe Splitting of S 2 ? On...

Describe Splitting of S 2 ? On inspiration: The split widens as both A, and Pi move away from each other with p, moving out more. The negative intrathoracic pressure during

Determine the quality of various food grains, Q. Determine the quality of v...

Q. Determine the quality of various food grains? After undertaking this activity, you will be able to: • determine the various fractions involved with the physical examinati

CONNECTING LINKS, HOW SHOULD I PREPARE AN INVESTIGATORY REPORT ON CONNECTIN...

HOW SHOULD I PREPARE AN INVESTIGATORY REPORT ON CONNECTING LINKS AS AN EVIDENCE OF EVOLUTION

How light reaction effects cell metabolism, How light reaction effects Cell...

How light reaction effects Cell Metabolism ? Light reactions :  The light reactions are carried out by two separate assemblies of several hundred chlorophyll molecules, acces

Subcutaneous nodules, These are found in about 3-6 per cent of cases of ARF...

These are found in about 3-6 per cent of cases of ARF. These nodules are typically subcutaneous, firm, painless, freely movable (0.5-2 cm size) and their presence indicates that t

Explain the term ferns, Explain the term Ferns? Ferns are plants that...

Explain the term Ferns? Ferns are plants that have vessels that conduct water, minerals, and nutrients, and reproduce through spores, rather than seeds. Ferns are therefore o

Inhibition might contribute to tumor formation, We now understand that muta...

We now understand that mutations that cause the inhibition of apoptosis are found in tumors. Because proliferation itself is not induced by the inhibition of apoptosis, explain how

Acute renal failure and its etiology, Acute Renal Failure You know tha...

Acute Renal Failure You know that acute renal failure refers to the sudden deterioration in kidney function, characterised by reduced urine excretion to less than 10 ml/kg  bo

Principles of nursing care, 1. Discuss how nursing has changed over the las...

1. Discuss how nursing has changed over the last two (2) decades. 2. Review and summarise the philosophy of your enrolled nurse course and its relevance to your clinical practic

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd