Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Supplementation for prevention of vitamin a deficiency, Define Supplementat...

Define Supplementation for prevention of vitamin A deficiency? Administration of large doses of vitamin A to children at risk has been the most popular approach to control nutr

Photosynthesis and cellular respiration, what cell organelle does photosynt...

what cell organelle does photosynthesis take place in?

Explain pancreatitis, Explain Pancreatitis Pancreatitis :- Inflammati...

Explain Pancreatitis Pancreatitis :- Inflammation of the pancreas.

In the phase when the cell is not dividing interphase, Q. In the phase when...

Q. In the phase when the cell is not dividing interphase is there activity within the cell nucleus? In the interphase there is intense metabolic activity in the cell nucleus th

Define standard or total plate counts (spc/tpc), Define Standard or Total P...

Define Standard or Total Plate Counts (SPC/TPC)? It is the most widely used method to know the microbiological quality of the food sample. It is quick and efficient method, giv

What food items include in full liquid diet, What food items  include in f...

What food items  include in full liquid diet -  Soups and broths -  Cereal porridges (refined cereals) -  Milk and milk beverages, yoghurt - Coffee, tea, fruit  juices

Type of fecundation that occur in arthropods, Q. What are the kinds of fecu...

Q. What are the kinds of fecundation that occur in arthropods? What is the predominant kind? In arthropods there are species having exterior fecundation and other species havin

What is exocytosis, Which of the following is true for exocytosis? A. D...

Which of the following is true for exocytosis? A. During exocytosis in skeletal muscle cells, there will be release of calcium ions from intracellular vesicles in the sarcoplas

Female reproductive system - graffian follicle, GRAFFIAN FOLLICLE - ...

GRAFFIAN FOLLICLE - It appears as knob or stigma in medulla. It is round, discovered by Graff. It is covered by 2 layers - thecae externa & theca interna. From theca i

What is a population, What is a population? The population is a set of ...

What is a population? The population is a set of individuals of the same species found in a given place in a given time.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd