Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Implantation, IMPLAN TA TIO N - Attachement of blastocyst on the ...

IMPLAN TA TIO N - Attachement of blastocyst on the endometrium of the uterus is called implantation. Generally it occurs 7th day after fertilisation. (6-10 days). Blas

Symptoms of oesophagitis, Q. Symptoms of oesophagitis? The symptoms of ...

Q. Symptoms of oesophagitis? The symptoms of oesophagitis include heartburn or pyrosis, iron-deficiency anaemia due to chronic tissue bleeding, aspiration, which may cause coug

What is growth monitoring of an infant, What is Growth Monitoring? In t...

What is Growth Monitoring? In third world countries, about half the children are short and underweight for their age. Inadequate nutrient intake is the main reason. Inadequate

Explain tetralogy of fallot repair and transposition, Explain Tetralogy of ...

Explain Tetralogy of fallot repair and Transposition of arteries? Tetralogy of Fallot Repair: This involves RV outflow resection, closure of the VSD and enlargement of the RV

Mechanisms of speciation, In the previous section we discussed the concept ...

In the previous section we discussed the concept of species in detail and concluded that the concept of biological species and Mayr's definition of species have a wide acceptance a

Explain adverse effects of voriconazole, Adverse Effects of voriconzole ...

Adverse Effects of voriconzole Transient visual disturbances, including blurred vision, photophobia and altered perception of color or image, are common with voriconazole. Rash

Evaluation of the programme or agency, Evaluation of the programme or agenc...

Evaluation of the programme or agency: It can be  based on following:  i)   Audit or review of programme or agency: This can be continuously done by the staff through in

Panting - temperature relations in animals, Normal 0 false fa...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

What are the major cells of the connective tissue proper, Q. What are the m...

Q. What are the major cells of the connective tissue proper? What is the name given to the intercellular material that surrounds these cells? The major cells of the connective

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd