Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Define alcoholic cardiomyopathy, Q. Define Alcoholic Cardiomyopathy? In...

Q. Define Alcoholic Cardiomyopathy? In a case of dilated cardiomyopathy alcohol cardiomyopathy is suspected if there is history of alcohol intake of 100g/day for more than 10

Phytochrome - development of plant, Phytochrome - Development of plant ...

Phytochrome - Development of plant You know that plants capture light energy during photosynthesis, now you are familiarised with another important and interesting role of lig

Why we not inundated with bacterial infections, We are told that every surf...

We are told that every surface we touch is teeming with bacterial cells, and bacteria are found in the pools we swim in, the water we wash with, and on the hands of friends. Why ar

Show protective structures of the central nervous system, Q. What are the p...

Q. What are the protective structures of the central nervous system present in vertebrates? In vertebrates the brain and the spinal cord are protected by membranes, the meninge

Lead, Le a d It is common cause of poisoning in cattle. Lead poisonin...

Le a d It is common cause of poisoning in cattle. Lead poisoning in other species is limited by reduced accessibility, more selective eating habits, or lower susceptibility.

Determine the number of gametes, An organism has 16 chromosomes in its soma...

An organism has 16 chromosomes in its somatic cells. Determine the number of gametes with different chromosome compositions that it can potentially create. Explain your answer. Ign

What do you understand by dimorphic nuclei, What do you understand by Dimor...

What do you understand by Dimorphic nuclei? Organization of the nuclear material typical of ciliates. There is always a single small micronucleus and either one large or many m

Joint, Ask question #Minimum 100 words what is joint accepted#

Ask question #Minimum 100 words what is joint accepted#

External factor - factor controlling metamorphosis in insect, External fact...

External factors - Factors Controlling Metamorphosis in Insects In few cases an external factor may be accountable for initiating moulting, as for instance in the blood su

Chromosomes, Chromosomes Karl Nageli and Hofmeister observed chr...

Chromosomes Karl Nageli and Hofmeister observed chromosomes in pollen mother cells of Tradescantia. Chromosome name proposed by Waldeyer. During cell division,

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd