Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Reducing pollution - conservation of wildlife, Reducing Pollution - Conserv...

Reducing Pollution - Conservation of wildlife As you already know, pollution of various kinds has affected the survival of living beings, particularly the wildlife in various

Involution - internalization of mesoderm, Involution - Internalization of M...

Involution - Internalization of Mesoderm As by now mentioned, in the frog Xenopus (and probably in other amphibian species as well) the cells of presumptive mesoderm are in t

Define requirements of carbohydrates during surgery, Define Requirements of...

Define Requirements of Carbohydrates during Surgery? Carbohydrates: Carbohydrates are needed to build up glycogen stores and spare the proteins for tissue synthesis, Around GO%

Assessment of tricuspid and pulmonary orifice areas, Assessment of Tricusp...

Assessment of Tricuspid and Pulmonary Orifice Areas Due to the rarity of tricuspid stenosis and pulmonary stenosis, no general agreement exists on what constitutes critical o

Explain about the protein-energy ratio, Explain about the Protein-Energy Ra...

Explain about the Protein-Energy Ratio (NDP Cal%)? Platt and his colleagues (1961) are largely responsible for the introduction of the ratio of protein energy to total energy (

Poultry and duck diseases-ranikhet disease, Ranikhet disease Ranikhet ...

Ranikhet disease Ranikhet disease, also known in the west as Newcastle disease, is a contagious and highly fatal disease of fowls caused by a virus of the genus Rubulavirus in

Erythrocytic cycle, Erythrocytic cycle The cycle that takes place i...

Erythrocytic cycle The cycle that takes place in the body of man who is considered as secondary host is called the erythrocytic cycle. The first stage of the cycle begins

Five kingdom classification, discuss the merits nd demerits of five kingdom...

discuss the merits nd demerits of five kingdom classification.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd