Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Human skeleton, HUMAN SKELETON - Hard supportive or protective elements...

HUMAN SKELETON - Hard supportive or protective elements of the animal body form the skeleton system. It's study in osteology. EXOSKELETO N - Present outside skin. It

Define that dna is the genetic material, How did Alfred Hershey and Martha ...

How did Alfred Hershey and Martha chase arrive at the conclusion that DNA is the Genetic material?

Skin, Two adaptation of the skin against attack by micro-organisms

Two adaptation of the skin against attack by micro-organisms

Determine the parts consists in our urinary system, Determine the parts con...

Determine the parts consists in Our urinary system Our urinary system consists of following:  Two kidneys  Two ureters  One urinary bladder  One urethra Apart fr

Explain the sticky films - food microbiology, Explain the Sticky Films - Fo...

Explain the Sticky Films - Food Microbiology? Sticky films or tape are pressed against the surface to be assessed. Exposed film/tape is then pressed on the agar plate and analy

Essay, Need an essay in regard to an experiment that I did. Essay Assignm...

Need an essay in regard to an experiment that I did. Essay Assignment: Experimental Design Now that you have completed several hands-on lab experiments, take a little time to con

Rabbit, reproductive system of rabbit

reproductive system of rabbit

Explain the clinical features of ps and vsd, Explain the Clinical Features ...

Explain the Clinical Features of PS and VSD ? Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Explain doctrine of signatures, Explain Doctrine of Signatures? Handed ...

Explain Doctrine of Signatures? Handed down from the ancients, and elaborated on by the herbalists, was the 'Doctrine of Signatures', which was based on features that resembled

Vegetative development - morphogenesis, Vegetative Development - Morphogene...

Vegetative Development - Morphogenesis This term is coined for the process leading to and determining the form and structure of organs. It is used mainly by experimental morph

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd