Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Mechanisms for response – protozoan, Mechanisms for Response – Protozoan ...

Mechanisms for Response – Protozoan Protozoa are sensitive to many kinds of stimuli like touch, temperature changes, light, chemicals, etc. It is not clear how they do so but

Phylum and chordata, phylum and chordata ex. and their classiication

phylum and chordata ex. and their classiication

Explain soybean protein, Explain soybean protein The need for the devel...

Explain soybean protein The need for the development of soybean protein concentrates stemmed primarily from two considerations: to enhance protein concentration and to improve

What is gum ghatti, What is Gum ghatti Gum ghatti, also known as Indian...

What is Gum ghatti Gum ghatti, also known as Indian gum, is amorphous, translucent exudates of the Anogeissus latifolia tree of the Combretaceae  family. Gum Ghatti is composed

Explain nutritional management of metabolic diseases, Q. Explain nutritiona...

Q. Explain nutritional management of metabolic diseases? The nutritional management of metabolic diseases such as gout and a few inborn errors of metabolism such as phenylketon

Define absorption, Define Absorption, Storage and Elimination of Vitamin D?...

Define Absorption, Storage and Elimination of Vitamin D? As we have already mentioned earlier, all fat-soluble vitamins share a common metabolic fate. Vitamin D is absorbed al

Work sheet, When the Balance Sheet column totals don't agree on the first a...

When the Balance Sheet column totals don't agree on the first attempt work backward through the process used in preparing the work sheet exclusively take the following steps until

How different are the respiration in fishes, How different are the respirat...

How different are the respiration in fishes and the respiration in adult amphibians? In fishes gas exchange is completed by direct contact of water with the branchiae (gills).

CONNECTING LINKS, HOW SHOULD I PREPARE AN INVESTIGATORY REPORT ON CONNECTIN...

HOW SHOULD I PREPARE AN INVESTIGATORY REPORT ON CONNECTING LINKS AS AN EVIDENCE OF EVOLUTION

Calorific value, Calorific value is one of the most important characteristi...

Calorific value is one of the most important characteristics of a fuel. It judges the efficiency of fuel. Calorific value is defined as "the total quantity of heat liberated, wh

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd