Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

How cereal and bread important for human -nutritional factor, How Cereal an...

How Cereal and Bread important for Human -Nutritional Factor? Cereals form the staple of the Indian diet. These grains are the main source of energy in the Indian diet

Cleaning efficiency of detergents and soaps, Q. Cleaning efficiency of Dete...

Q. Cleaning efficiency of Detergents and Soaps? Soaps and detergents emulsify fats, oils and grease so that they are easily washed away. They usually contain chemical builder

Psychosocial problems, PSYCHOSOCIA L PROBLEMS  - 1 .       Accidental...

PSYCHOSOCIA L PROBLEMS  - 1 .       Accidental injury - Automobile accidents are no. 1 killers of adolescents, as they drive often fast. 2 .       Depression - I

Cycles of matter, describe the path of nitrogen through its biogenochemicsa...

describe the path of nitrogen through its biogenochemicsal cycle

Explain the working of skeletal muscle, Explain the working of Skeletal Mus...

Explain the working of Skeletal Muscle? Skeletal muscle is under voluntary control and is responsible for voluntary movements of body parts. Skeletal muscle is also called stri

Determine the symptoms of bacillus cereus, Determine the Symptoms of bacill...

Determine the Symptoms of bacillus cereus Extremely large numbers (10 8 per gram) of viable cells of B. cereus must be ingested to develop signs and symptoms of the syndrome.

Explain high fibre diets, High fibre diets High fibre  diets: The pat...

High fibre diets High fibre  diets: The patients  are advised  to  eat  high  fibre cereals as whole grain flour and bread, whole grain bread cereals, whole wheat pasta and b

Excretion, How will the urine concentration be affected if the henle''s loo...

How will the urine concentration be affected if the henle''s loop of a person is removed and his PCT is joined directly with DCT?

Predict whether narrowing or widening of the blood vessels, Body temperatur...

Body temperature is homeostatic ally regulated around a set point. Given your knowledge of negative feedback and homeostatic control system, predict whether narrowing or widening o

Water relations in terrestrial environment, Water Relations in Terrestrial ...

Water Relations in Terrestrial Environment Insects are the largest group of metazoans which have most successfully invaded the terrestrial environment. In addition, most arach

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd