Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Genetics , write about complementary genes

write about complementary genes

Risk factor modification, Risk Factor Modification :  Even after CABG,...

Risk Factor Modification :  Even after CABG, patients are at risk of progression of native coronary artery disease and development of lesions in the conduits. Modification of

PROTOZOA, WHAT IS THE CLASSIFICATION OF PROTOZOA ..

WHAT IS THE CLASSIFICATION OF PROTOZOA ..

Stress testing after myocardial infraction, Q. Stress Testing after Myocard...

Q. Stress Testing after Myocardial Infraction? Many post infarction deaths are sudden and occur with in the first 6 months after infarction. Exercise testing from 10 days to we

What are the cell types that form the phloem, What are the cell types that ...

What are the cell types that form the phloem? What are the main features of those cells? The major cells that form the phloem are the sieve elements and the companion cells. Th

Features of phylum porifera and eumetazoa, Features of Phylum Porifera and ...

Features of Phylum Porifera and Eumetazoa Table: Distinctive Features of Phylum Porifera and Eumetazoa The branch Eumetazoa, as we have seen above, consist of meta

Describe organs of female reproductive system, Q. What are the organs that ...

Q. What are the organs that are part of the female reproductive system? The organs that constitute the female reproductive system are the ovaries, the uterus, the Fallopian tub

Polyarthritis, Polyarthritis  1)  Gonococcal - Therapeutic trial of penc...

Polyarthritis  1)  Gonococcal - Therapeutic trial of pencillin may help in diagnosis of gonococcal  infection.  2)  Viral infections such as rubella and hepatitis B may have

Feline panleukopenia, Feline panleukopenia It is arguably the most importa...

Feline panleukopenia It is arguably the most important of all feline viral diseases and all members of the family Felidae are susceptible. This disease is commonly found in kitten

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd