Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

What is the heterotrophic hypothesis on the origin of life, What is the het...

What is the heterotrophic hypothesis on the origin of life? As per to the heterotrophic hypothesis the first living beings were very simple heterotrophic organisms that is not

State diagnosis and prevention of vibrio parahaemolyticus, State the Diagno...

State the Diagnosis and prevention of VIBRIO PARAHAEMOLYTICUS Diagnosis: Diagnosis of gastroenteritis caused by this organism is made by  culturing the organism from the diarrh

Phenology of different species, Phenology of Different Species The phe...

Phenology of Different Species The phenology of different species present in a community may differ from each other significantly. It is these phenological changes which give

Epidemiology, Endocarditis usually occurrs more frequently in men, gender d...

Endocarditis usually occurrs more frequently in men, gender derived ratios range from 1.6 to 2.5. The age specific incidence of endocarditis increased progressively after 30 years

State the swinging flashlight test, State the Swinging Flashlight Test ...

State the Swinging Flashlight Test The patient looks into the distance while the examiner shines a bright light first into one eye for a few seconds and then the other. As the

Head examination of new born, Head - check for size, shape or fontan...

Head - check for size, shape or fontanelles, caput, or any other abnormality. Fontanel - anterior fontanel is diamond shaped having size of 2.5 - 4.5 cms. It close

Biodiversity as products, Individual components of biodiversity provide an ...

Individual components of biodiversity provide an unbeliev able wide range of products that are used to enhance the lives of people in all countries of the world. It is the diversit

Determine the factors affecting fertilizer requirements, Factors Affecting ...

Factors Affecting Fertilizer Requirements   The rapid increase in the use of fertilizers is based on the fact that large profits are obtained from the money invested in them. The

What is the kind of life cycle present in pteridophytes, Q. What is the kin...

Q. What is the kind of life cycle present in pteridophytes? Like all plants pteridophytes present diplobiontic (alternation of metagenesis or generations,) life cycle.

What is pollination, What is pollination? What are the main forms of pollin...

What is pollination? What are the main forms of pollination? The process in which pollen grains (the male gametophytes of phanerogamic plants) reach the female gametophyte is k

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd