Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Measures of evenness, Measures of Evenness The maximum Shannon-Wiener i...

Measures of Evenness The maximum Shannon-Wiener index for a given number of species can be calculated as: The minimum Shannon-Wiener index for a given data set can be c

Explain the difference among dna primase and dna polymerase, Which of the f...

Which of the following is not a difference among DNA primase and DNA polymerase? A. DNA primase can initiate replication of DNA de novo whereas DNA polymerase needs a short oli

How different are the heart chambers, Q. Concerning the thickness of their ...

Q. Concerning the thickness of their walls how different are the heart chambers? The ventricle walls are thicker than the atrium walls since ventricles are structures responsib

Explain injection rate and volume, Q. Explain Injection Rate and Volume? ...

Q. Explain Injection Rate and Volume? This is best achieved by injecting directly into the ventricular chamber. Midcavitary position of the catheter ensures that there is no ve

D-glucose exists in all of the forms except, As a result of mutarotation, D...

As a result of mutarotation, D-glucose exists in all of the following forms EXCEPT: Select one: a. L-glucopyranose. b. alpha-anomer. c. free aldehyde (linear) d. bet

Explain conservative substitution, Conservative Substitution: The nucleoti...

Conservative Substitution: The nucleotide mutation that alters the amino acid sequence of protein, but which causes substitution of one amino acid with another which has a side ch

Explain micafungin, Explain Micafungin It is an echinocandin indicated ...

Explain Micafungin It is an echinocandin indicated for treatment of esophageal candidiasis and prophylaxis of invasive Candida infections in patients undergoing hematopoietic s

Define lipids - tests for presence of exoenzymatic activity, Define Lipids ...

Define Lipids - Tests for Presence of Exoenzymatic Activity? Lipids are also high molecular weight compounds. Enzyme lipases (esterases) cleaves the ester bond to form glycerol

Ichnology, Ichnology :  This is the study of foot prints. Ichnology is a ty...

Ichnology :  This is the study of foot prints. Ichnology is a type of branch of geology which deals with traces of organismal behavior like as burrows or footprints. It is commonly

Define primary level care - public nutrition, Define Primary Level Care - P...

Define Primary Level Care - Public Nutrition? This is the first level of contact of an individual, the family and the community with the national health system. It is possible

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd