Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Define transcellular fluid compartment - extracellular fluid, Define transc...

Define transcellular fluid compartment - extracellular fluid? The transcellular fluid is a small compartment that represents all those body fluids which are formed from the tra

Mention chemical agents available for sterilization, Q. Mention chemical ag...

Q. Mention chemical agents available for sterilization? Various chemical agents available for sterilization are: Alcohols: ethyl alcohol, isopropyl alcohol, trichlorobuta

Explain evidence of coverage of ecology, Explain Evidence of coverage of Ec...

Explain Evidence of coverage of Ecology Evidence of coverage of Ecology and Evolution to the level of Descriptor 2 and an evaluation or  discussion that shows depth of underst

What is the approximate number of amino acids, What would be the approximat...

What would be the approximate number of amino acids of a protein with a mass of 203 kd? Assume an average molecular weight for amino acids of 110 grams/mol.

Describe the developmental periods of coronary artery diseas, Describe the ...

Describe the Developmental Periods of coronary artery diseases? The development of coronary artery disease like many other diseases can be divided into the following periods:

Classification of aquatic organisms, Classification of Aquatic Organisms ...

Classification of Aquatic Organisms After discussing the common types of the aquatic ecosystem let us now study in brief the ecological classification of aquatic organisms. I

Excretory system, what is the excretory organ of a lizard?

what is the excretory organ of a lizard?

Main cytoplasmic structures present in animal cells, What are the main cyto...

What are the main cytoplasmic structures present in animal cells? Ans) The major cytoplasmic structures of the cell are the centrioles, the cytoskeleton, lysosomes, mitochondria

Factors influencing uptake from lumen to intestinal cells, Define Factors ...

Define Factors influencing  uptake from lumen to intestinal cells? inhibition by intrinsic matrix, inhibition by dietary fiber sources, differential crowding by

Endosperm, 1. What are the examples of helobial endosperm

1. What are the examples of helobial endosperm

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd