Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Determine the term clade, Determine the term Clade? In cladistic taxono...

Determine the term Clade? In cladistic taxonomy, how groups of animals are related to each other. It includes the ancestral group and all of the other groups, or lineages, of a

What happens within the cell in the first interface period, What are the ev...

What are the events that mark the beginning and the end of the first interphase period? What happens within the cell in this period? The first interphase period is the G1. It s

Calcium - mineral elements, CALCIUM It is the most abundant mineral of...

CALCIUM It is the most abundant mineral of animal body. Calcium is available in all types of vegetables, grain, milk, cheese, eggs, fish and butter. By its deficiency r

What is rearrangement reaction, PREPARATION OF BENZILIC ACID 1.  What i...

PREPARATION OF BENZILIC ACID 1.  What is rearrangement reaction? The reactions in which the carbon of the molecule is rearranged to give a structural isomer of the original

Assignment, parts involving in circulatory system

parts involving in circulatory system

What will happen without enough insulin, Q. What will happen without enough...

Q. What will happen without enough insulin? Without enough insulin two things can happen. Firstly, the cells of the body will be unable to use the glucose in the blood for ener

Cornea - organogenesis of eye and limb, Cornea - Organogenesis of Eye a...

Cornea - Organogenesis of Eye and Limb The fully formed cornea contains 2-cell layered epithelium and the stroma made of extra cellular secreted materials. The bulk of the

Names and uses of the various laboratory tools, What are the names and uses...

What are the names and uses of the various laboratory tools? Tools are beakers, microscopes, tweezers, hot plates, lasers, test tubes, voltmeters, Erlenmeyer flasks, thermomete

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd