Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Define proteins as regulators of water balance, Define Proteins as regulato...

Define Proteins as regulators of water balance? As substrates and solutes are transferred or exchanged across membranes, water has a tendency to follow to maintain equal osmoti

Determine the stage 1 implant surgery, Determine the stage 1 implant surger...

Determine the stage 1 implant surgery Following stage 1 surgery, prior to commencing on the prosthetic procedures in the conventional loading protocol it is critical that the s

Agro industrial-animal wastes, Animal wastes Large quantities of anima...

Animal wastes Large quantities of animal wastes are available in the country but generally they are low in nutrient content with poor feeding value to the animals. However, po

Define exocytosis , A cell frequently wants to secrete larger molecule...

A cell frequently wants to secrete larger molecules than can be accommodated through the transport systems dealt with in Topic E3. Exocytoses get to the movement of proteins out of

What is the significance of the epiglottis in human body, What is the signi...

What is the significance of the epiglottis in human body? What happens to the glycogen concentration in the liver cells when the level of adrenaline enhances in the blood strea

Explain about the epilepsy, Explain about the Epilepsy? Epilepsy is a n...

Explain about the Epilepsy? Epilepsy is a neuromuscular disorder in which transient seizures recur due to an abnormal brain activity. The brain, through all orderly electric ex

What is glucose tolerance test, Q. What is Glucose Tolerance Test? Gluc...

Q. What is Glucose Tolerance Test? Glucose Tolerance Test (GTT) is used for diagnosis of diabetes mellitus. In this test, blood sugar levels are measured after giving glucose

How do the bacteria reproduce, Q. How do the bacteria reproduce? Bacter...

Q. How do the bacteria reproduce? Bacteria reproduce by binary fission termed as scissiparity. Some bacteria however present a kind of sexual reproduction transformation, conju

Blood pressure, bloodpressure will be more in _ in than in_

bloodpressure will be more in _ in than in_

Explain carboxypeptidase, Carboxypeptidase The  inactive  zymogen  proc...

Carboxypeptidase The  inactive  zymogen  procarboxypeptidase  is  activated  by  trypsin .The further action on the polypeptides is carried out by carboxypeptidase which  attac

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd