Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Asexual reproduction that occurs in hydras, Q. What is the kinds of asexual...

Q. What is the kinds of asexual reproduction that occurs in hydras? Hydras reproduce asexually by budding.

Relationship between the ovulation and menstrual cycle, Q. What is the rela...

Q. What is the relationship between the ovulation and menstrual cycle? Ovulation is the releasing of the female gamete from the ovary and Ovulation is a periodical event that o

Why are heterotrophic not classified as plants or animals, Why are heterotr...

Why are heterotrophic, autotrophic , and mixotrophic protists not classified as plants or animals ?

Give a specific example of homeostasis, Give a specific example of homeosta...

Give a specific example of homeostasis An owl handles its body temperature by burning fuel to make body heat and by fluffing up its feathers to trap an insulating layer of air

Syncytial theory - metazoa, Syncytial Theory - Metazoa This theory su...

Syncytial Theory - Metazoa This theory suggests that the ancestral metazoan was at ,first Syncytial in structure but later became cellularised by formation of cell membranes

#titlecylintreta.., Aiscommoncellismwhatsk question #Minimum 100 words acce...

Aiscommoncellismwhatsk question #Minimum 100 words accepted#

Myofilaments of myofibrils, Normal 0 false false false ...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

What is nidation, What is nidation? In which phase of the menstrual cycle d...

What is nidation? In which phase of the menstrual cycle does nidation occur? Nidation is the implantantion of the embryo in the uterus. Nidation happens around the 7th day afte

Define effect of enery on quality and quantity of human milk, Define Effect...

Define Effect of Enery on quality and quantity of human milk? Energy: In case of chronic under nutrition, an association between postpartum weight loss and lower energy transfe

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd