Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Define low - density lipoprotein, Q. Define Low - density lipoprotein? ...

Q. Define Low - density lipoprotein? Ans. LDL is the major cholesterol-rich lipoprotein carrying approximately 70 per cent of plasma cholesterol. It serves to transport ch

Illustrate the respiratory system, Illustrate the Respiratory System In...

Illustrate the Respiratory System In general, respiration and breathing are understood to be same. But it is not so. Breathing simply means taking in oxygen from air and giving

What is fixism?, What is fixism? The Fixism is the theory about the div...

What is fixism? The Fixism is the theory about the diversity of life on earth that affirms that the current existent species were identical to species of the past and came out

Auditing, Definition of auditing According to the International Sta...

Definition of auditing According to the International Standard on Auditing (ISA) No. 200 Objective and common Principles Governing an Audit of Financial Statements, the obj

Explain why the pigs in the f2 generation, If you create an F2 generation b...

If you create an F2 generation by mating two of the F1 offspring from your cross of a pure-bred brown pig with a pure-bred heavy spotted red pig. Explain why the pigs in your F2 ge

Ascus, what is ascus ?

what is ascus ?

Epithelial cells of the kidney proximal tubule, Which of the following is t...

Which of the following is true for the epithelial cells of the kidney proximal tubule? A. The sodium-glucose co-transporter in the luminal membrane is responsible for the net f

Dissolved gases and alkalinity, Dissolved Gases and Alkalinity Disso...

Dissolved Gases and Alkalinity Dissolved Gases The marine environment serves as a gigantic reservoir of dissolved oxygen and carbon dioxide, which respectively help reg

Admission of mentally patient, Admission of Mentally Patient: Volunt...

Admission of Mentally Patient: Voluntary Basis  (Voluntary Admission)   Any adult person who considers himself  to be mentally ill, can  request  the Medical Officer for

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd