Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Examining regulated health professions, In a comparative study you are exam...

In a comparative study you are examining two items, two scenarios, for Introduction to Professionalism you will be Examining two Regulated Health Professions. One will be the Colle

Method of cloning dna fragments into plasmids, During our discussion of rep...

During our discussion of replication origins we took a step-by-step look at the method of cloning DNA fragments into plasmids . Based on your knowledge of this discussion which

Define the solar concentration, Define the Solar Concentration? As in ...

Define the Solar Concentration? As in food dehydration, one of the simplest methods of evaporating water is with solar energy. A typical example of this method is production a

What''s the difference between heterozygosity & homozygosity, What is the d...

What is the difference between heterozygosity and homozygosity? The Homozygosity occurs when an individual has two identical alleles of a gene, for instance, AA or aa. The Het

Carbohydrates requirement in pectic ulcer, Q. Carbohydrates requirement in ...

Q. Carbohydrates requirement in pectic ulcer? Carbohydrates: These should provide around 55 to 65% of the daily intake. Emphasis - J should be laid on the consumption of 60th s

Photoperiodism was first characterised, Photoperiodism was first characteri...

Photoperiodism was first characterised in : 1. Tobacco 2. Potato 3. Tomato 4. Cotton Tobacco is the first in whic photoperiodism characterised.

Unicellular organisms, How was it proved in the case of Amoeba that the key...

How was it proved in the case of Amoeba that the key to the life of a cell is Nucleus?

Explain some characteristic features of mucor, Explain some Characteristic ...

Explain some Characteristic Features of Mucor? 1. Stolons characteristics of Rhizopus are absent in Mucor. The aerial mycelium in Mucor consists of branched hyphae, which grow

Explain the management of renewable resources, Explain the Management of Re...

Explain the Management of Renewable Resources? Since the human population has grown, human impacts on the resources that we use, like fisheries and forests, have continued to g

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd